The burden of respiratory syncytial virus lower respiratory tract disease in infants in the United States: a synthesis

EAF Simões - The Journal of Infectious Diseases, 2022 - academic.oup.com
Although pediatricians have long recognized that respiratory syncytial virus (RSV) is the
single most important cause of lower respiratory tract infection (LRTI) in infants and young …

[HTML][HTML] The efficacy and safety of nirsevimab for the prevention of RSV infection among infants: a systematic review and meta-analysis

MWR Turalde-Mapili, JAL Mapili, CWR Turalde… - Frontiers in …, 2023 - frontiersin.org
Background Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality
among infants with a global incidence of 9.5% and a mortality rate of 2.2%. The …

[HTML][HTML] Cost-effectiveness analysis of nirsevimab and maternal RSVpreF vaccine strategies for prevention of Respiratory Syncytial Virus disease among infants in …

A Shoukat, E Abdollahi, AP Galvani… - The Lancet Regional …, 2023 - thelancet.com
Background The cost-effectiveness of immunisation strategies with a long-acting
monoclonal antibody (nirsevimab) and/or a protein-based maternal vaccine (RSVpreF) for …

[HTML][HTML] Monoclonal antibodies for prophylaxis and therapy of respiratory syncytial virus, SARS-CoV-2, human immunodeficiency virus, rabies and bacterial infections …

S Esposito, G Amirthalingam, M Bassetti… - Frontiers in …, 2023 - frontiersin.org
Monoclonal antibodies (mABs) are safe and effective proteins produced in laboratory that
may be used to target a single epitope of a highly conserved protein of a virus or a bacterial …

Nirsevimab: review of pharmacology, antiviral activity and emerging clinical experience for respiratory syncytial virus infection in infants

SCJ Jorgensen - Journal of Antimicrobial Chemotherapy, 2023 - academic.oup.com
Respiratory syncytial virus (RSV) is a leading cause of hospitalization and infant mortality
worldwide. There are currently no approved vaccines against RSV, and immunoprophylaxis …

[HTML][HTML] Cost-effectiveness of respiratory syncytial virus preventive interventions in children: a model comparison study

X Li, D Hodgson, J Flaig, A Kieffer, WL Herring… - Value in health, 2023 - Elsevier
Objectives Model-based cost-effectiveness analyses on maternal vaccine (MV) and
monoclonal antibody (mAb) interventions against respiratory syncytial virus (RSV) use …

[HTML][HTML] Hospitalization for bronchiolitis in children aged≤ 1year, Southern Italy, year 2021: need for new preventive strategies?

ME Baldassarre, D Loconsole, F Centrone… - Italian journal of …, 2023 - Springer
Background Bronchiolitis is a major cause of hospitalization in infants, particularly in the first
six months of life, with approximately 60–80% of admissions due to respiratory syncytial …

Respiratory syncytial virus disease in young children and older adults in Europe: a burden and economic perspective

EAF Simões - The Journal of Infectious Diseases, 2022 - academic.oup.com
Soon after the discovery that respiratory syncytial virus (RSV) was the major cause of
bronchiolitis in infants, in 1956 [1], vaccines were developed to try and prevent both infection …

[HTML][HTML] Outpatient respiratory syncytial virus infections and novel preventive interventions

SF Hak, RP Venekamp, JG Wildenbeest… - Current Opinion in …, 2024 - journals.lww.com
Novel RSV immunizations hold promise to reduce the RSV burden in infants, with
substantial impact on everyday practice. Tailored parental guidance will be instrumental for …

[HTML][HTML] Does nirsevimab prevent lower respiratory infections caused by respiratory syncytial virus?

K Sullivan, B Sullivan - Journal of Perinatology, 2024 - nature.com
Setting The study enrolled participants in the northern hemisphere in 2019 (150 sites in 20
countries) and the southern hemisphere in 2020 (10 sites in 1 country). Patient enrollment …