Multiple endocrine neoplasia type 1 (MEN1): an update and the significance of early genetic and clinical diagnosis

CDC Kamilaris, CA Stratakis - Frontiers in endocrinology, 2019 - frontiersin.org
Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in
an autosomal dominant manner and characterized by a predisposition to a multitude of …

Multiple endocrine neoplasia type 1 and the pancreas: diagnosis and treatment of functioning and non-functioning pancreatic and duodenal neuroendocrine …

B Niederle, A Selberherr, DK Bartsch, ML Brandi… - …, 2021 - karger.com
The better understanding of the biological behavior of multiple endocrine neoplasia type 1
(MEN1) organ manifestations and the increase in clinical experience warrant a revision of …

Consensus: guidelines for diagnosis and therapy of MEN type 1 and type 2

ML Brandi, RF Gagel, A Angeli… - The Journal of …, 2001 - academic.oup.com
This is a consensus statement from an international group, mostly of clinical
endocrinologists. MEN1 and MEN2 are hereditary cancer syndromes. The commonest …

Inherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversies

RT Jensen, MJ Berna, DB Bingham, JA Norton - Cancer, 2008 - Wiley Online Library
Pancreatic endocrine tumors (PETs) have long fascinated clini-cians, because some can
release biologically active hormones that cause distinct syndromes and provide important …

Update on the clinical management of multiple endocrine neoplasia type 1

CRC Pieterman, GD Valk - Clinical Endocrinology, 2022 - Wiley Online Library
This review provides an overview of novel insights in the clinical management of patients
with Multiple Endocrine Neoplasia Type 1, focusing on the last decade since the last update …

Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with …

T Ito, H Igarashi, H Uehara, MJ Berna, RT Jensen - Medicine, 2013 - journals.lww.com
Multiple endocrine neoplasia type 1 (MEN1) is classically characterized by the development
of functional or nonfunctional hyperplasia or tumors in endocrine tissues (parathyroid …

Multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome: a prospective study of 107 cases and comparison with 1009 cases from the literature

F Gibril, M Schumann, A Pace, RT Jensen - Medicine, 2004 - journals.lww.com
In patients with multiple endocrine neoplasia type 1 (MEN1), the most common functional
pancreatic endocrine tumor (PET) syndrome is Zollinger-Ellison syndrome (ZES). ZES has …

Epidemiology data on 108 MEN 1 patients from the GTE with isolated nonfunctioning tumors of the pancreas

F Triponez, D Dosseh, P Goudet, P Cougard… - Annals of …, 2006 - journals.lww.com
Objective: To analyze the penetrance and clinical course of isolated nonfunctioning tumors
of the pancreas (NFTP) in MEN 1 patients, and to propose a strategy for managing them …

Prospective study of thymic carcinoids in patients with multiple endocrine neoplasia type 1

F Gibril, YJ Chen, DS Schrump… - The Journal of …, 2003 - academic.oup.com
Little is known of the natural history of thymic carcinoids in multiple endocrine neoplasia type
1 (MEN1). This is important because in 1993 they were identified as a frequent cause of …

Long-term natural course of pituitary tumors in patients with MEN1: results from the DutchMEN1 Study Group (DMSG)

JM De Laat, OM Dekkers… - The Journal of …, 2015 - academic.oup.com
Context: Guidelines advise lifelong radiological followup for asymptomatic pituitary
adenomas (PITs) because of the risk for growth and subsequent visual field defects. In the …