A randomized, controlled clinical trial was performed with patients with acute respiratory
distress syndrome (ARDS) to compare the effect of conventional therapy or inhaled nitric …

Purpose To evaluate the effects of acute hypercapnia induced by positive end-expiratory
pressure (PEEP) variations at constant plateau pressure (P plat) in patients with severe …

This pilot randomized controlled clinical trial of patients with ARDS was implemented to
study the impact of inhaled nitric oxide (inhNO) on lung function, morbidity, and mortality …

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Background Nitric oxide inhibits platelet adhesion and aggregation in vitro. The aim of this
prospective study was to assess the platelet antiaggregating activity of nitric oxide …

The goal of this study was to assess lung morphology in patients with acute lung injury
according to the presence or the absence of a lower inflection point (LIP) on the lung …

Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, has been shown to decrease
pulmonary artery pressures but not increase cardiac output in hemodynamically stable …

Lung-protective ventilation (LPV) has become the cornerstone of management in patients
with ARDS. A subset of patients is unable to tolerate LPV without significant CO 2 elevation …

Pulmonary hypertension (PH) is a characteristic feature of the acute respiratory distress
syndrome (ARDS). The magnitude of PH has been shown to correlate with the severity of …

Background Inhaled nitric oxide (iNO) has been used for treatment of acute respiratory
failure and pulmonary hypertension since 1991 in adult patients in the perioperative setting …