SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Airborne transmission of respiratory viruses

CC Wang, KA Prather, J Sznitman, JL Jimenez… - Science, 2021 - science.org
BACKGROUND Exposure to droplets produced in the coughs and sneezes of infected
individuals or contact with droplet-contaminated surfaces (fomites) have been widely …

[HTML][HTML] Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

B Killingley, AJ Mann, M Kalinova, A Boyers… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …

[PDF][PDF] Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb

M Khan, SJ Yoo, M Clijsters, W Backaert, A Vanstapel… - Cell, 2021 - cell.com
Anosmia, the loss of smell, is a common and often the sole symptom of COVID-19. The onset
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …

[PDF][PDF] Temporal Profiles of Antibody Responses, Cytokines, and Survival of COVID-19 Patients: A Retrospective Cohort in Wuhan, China

L Liu, HG Chen, Y Li, H Li, J Li… - Eng …, 2021 - devp-service.oss-cn-beijing.aliyuncs …
abstract The longitudinal immunologic status of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)-infected patients and its association with the clinical outcome …

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

NL Welch, M Zhu, C Hua, J Weller, ME Mirhashemi… - Nature Medicine, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear
need for high-throughput, multiplexed and sensitive assays for detecting severe acute …

An evidence review of face masks against COVID-19

J Howard, A Huang, Z Li, Z Tufekci… - Proceedings of the …, 2021 - National Acad Sciences
The science around the use of masks by the public to impede COVID-19 transmission is
advancing rapidly. In this narrative review, we develop an analytical framework to examine …

Mechanisms of SARS-CoV-2 transmission and pathogenesis

AG Harrison, T Lin, P Wang - Trends in immunology, 2020 - cell.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) marks
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …

[PDF][PDF] Case study: prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised individual with cancer

VA Avanzato, MJ Matson, SN Seifert, R Pryce… - Cell, 2020 - cell.com
Long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding was
observed from the upper respiratory tract of a female immunocompromised individual with …

[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19

B Hu, H Guo, P Zhou, ZL Shi - Nature Reviews Microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …