Take-home naloxone for the emergency interim management of opioid overdose: the public health application of an emergency medicine

J Strang, R McDonald, G Campbell, L Degenhardt… - Drugs, 2019 - Springer
Naloxone is a well-established essential medicine for the treatment of life-threatening
heroin/opioid overdose in emergency medicine. Over two decades, the concept of 'take …

Does naloxone provision lead to increased substance use? A systematic review to assess if there is evidence of a 'moral hazard'associated with naloxone supply

WC Tse, F Djordjevic, V Borja, L Picco, T Lam… - International Journal of …, 2022 - Elsevier
Background Take home naloxone (THN) programs have been rapidly upscaled in response
to increasing opioid-related mortality. One often cited concern is that naloxone provision …

Modelling the combined impact of interventions in averting deaths during a synthetic‐opioid overdose epidemic

MA Irvine, M Kuo, JA Buxton, R Balshaw… - …, 2019 - Wiley Online Library
Background and aims The province of British Columbia (BC) Canada has experienced a
rapid increase in illicit drug overdoses and deaths during the last 4 years, with a provincial …

Evaluation of a fentanyl drug checking service for clients of a supervised injection facility, Vancouver, Canada

M Karamouzian, C Dohoo, S Forsting, R McNeil… - Harm reduction …, 2018 - Springer
Abstract Background British Columbia, Canada, is experiencing a public health emergency
related to opioid overdoses driven by consumption of street drugs contaminated with illicitly …

[HTML][HTML] Reasons people who use opioids do not accept or carry no-cost naloxone: qualitative interview study

AS Bennett, R Freeman, DC Des Jarlais… - JMIR formative …, 2020 - formative.jmir.org
Background: Many people use opioids and are at risk of overdose. Naloxone is an opioid
antagonist used to counter the effects of opioid overdose. There is an increased availability …

Naloxone's role in the national opioid crisis—past struggles, current efforts, and future opportunities

AS Bennett, L Elliott - Translational Research, 2021 - Elsevier
Over the past 25 years, naloxone has emerged as a critical lifesaving overdose antidote.
Public health advocates and community activists established early methods for naloxone …

[HTML][HTML] Effects of naloxone distribution to likely bystanders: results of an agent-based model

C Keane, JE Egan, M Hawk - International Journal of Drug Policy, 2018 - Elsevier
Background Opioid overdose deaths in the US rose dramatically in the past 16 years,
creating an urgent national health crisis with no signs of immediate relief. In 2017, the …

Beliefs and misperceptions about naloxone and overdose among US laypersons: a cross-sectional study

J Agley, Y Xiao, L Eldridge, B Meyerson… - BMC Public Health, 2022 - Springer
Background Overdose education and naloxone distribution (OEND) to laypersons are key
approaches to reduce the incidence of opioid-involved overdoses. While some research has …

“I didn't want to be on suboxone at first…”–Ambivalence in perinatal substance use treatment

B Ostrach, C Leiner - Journal of Addiction Medicine, 2019 - journals.lww.com
Objectives: The objectives of this article are to present findings from recent qualitative
research with patients in a combined perinatal substance use treatment program in Central …

Concerns that an opioid antidote could “make things worse”: Profiles of risk compensation beliefs using the Naloxone-Related Risk Compensation Beliefs (NaRRC-B) …

RP Winograd, KB Werner, L Green… - Substance …, 2020 - journals.sagepub.com
Background and aims: As opioid overdose death rates reach epidemic proportions in the
United States, the widespread distribution of naloxone is imperative to save lives. However …