Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Photobiomodulation (PBM) involves the use of red or near‐infrared light at low power
densities to produce a beneficial effect on cells or tissues. PBM therapy is used to reduce …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

The mammalian genome encodes 28 distinct members of the transient receptor potential
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …

Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …

Transient Receptor Potential (TRP) channels are a family of ion channels whose members
are distributed among all kinds of animals, from invertebrates to vertebrates. The importance …

Despite a significant focus on the photochemical and photoelectrical mechanisms
underlying photobiomodulation (PBM), its complex functions are yet to be fully elucidated …

Peripheral detection of nociceptive and painful stimuli by sensory neurons involves a
complex repertoire of molecular detectors and/or transducers on distinct subsets of nerve …

Phospholipase C-mediated hydrolysis of phosphatidylinositol 4, 5-bisphosphate generates
diacylglycerol, inositol 1, 4, 5-trisphosphate and protons, all of which can regulate TRPV1 …

Specialized receptors belonging to the transient receptor potential (TRP) family of ligand-
gated ion channels constitute the critical detectors and transducers of pain-causing stimuli …