Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Exosomes: A potential tool for immunotherapy of ovarian cancer
X Gong, H Chi, DF Strohmer, AT Teichmann… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor of the female reproductive system, with a very poor
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …
Integrated “lab-on-a-chip” microfluidic systems for isolation, enrichment, and analysis of cancer biomarkers
The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …
the early detection, molecular characterization and monitoring of cancer over the past …
Microfluidics‐based molecular profiling of tumor‐derived exosomes for liquid biopsy
Y Wang, S Wang, L Li, Y Zou, B Liu, X Fang - View, 2023 - Wiley Online Library
Exosomes are extracellular vesicles that actively secreted by most live cells via endosome
pathway. They distribute ubiquitously in body fluids and play important roles in physiological …
pathway. They distribute ubiquitously in body fluids and play important roles in physiological …
Extracellular Vesicle (EVs) associated non-coding RNAs in lung cancer and therapeutics
A Paramanantham, R Asfiya, S Das, G McCully… - International journal of …, 2022 - mdpi.com
Lung cancer is one of the most lethal forms of cancer, with a very high mortality rate. The
precise pathophysiology of lung cancer is not well understood, and pertinent information …
precise pathophysiology of lung cancer is not well understood, and pertinent information …
Exosome-transmitted circ_002136 promotes hepatocellular carcinoma progression by miR-19a-3p/RAB1A pathway
P Yuan, J Song, F Wang, B Chen - BMC cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) are enriched in exosomes and are
extremely stable. Exosome-mediated intercellular transfer of specific biologically active …
extremely stable. Exosome-mediated intercellular transfer of specific biologically active …
Thiolate DNAzymes on gold nanoparticles for isothermal amplification and detection of mesothelioma-derived exosomal PD-L1 mRNA
Catalytic DNAzymes have been used for isothermal amplification and rapid detection of
nucleic acids, holding the potential for point-of-care testing applications. However, when …
nucleic acids, holding the potential for point-of-care testing applications. However, when …
Therapeutic potential of RNA-enriched extracellular vesicles: the next generation in RNA delivery via biogenic nanoparticles
M Muskan, P Abeysinghe, R Cecchin, H Branscome… - Molecular Therapy, 2024 - cell.com
Exosomes are extracellular vesicles (EVs)(∼ 50–150 nm) that have emerged as promising
vehicles for therapeutic applications and drug delivery. These membrane-bound particles …
vehicles for therapeutic applications and drug delivery. These membrane-bound particles …
Potential therapeutic and diagnostic approaches of exosomes in multiple sclerosis pathophysiology
N Hasaniani, S Nouri, M Shirzad, S Rostami-Mansoor - Life Sciences, 2024 - Elsevier
Exosomes are bilayer lipid vesicles that are released by cells and contain proteins, nucleic
acids, and lipids. They can be internalized by other cells, inducing inflammatory responses …
acids, and lipids. They can be internalized by other cells, inducing inflammatory responses …
Emerging micro-nanotechnologies for extracellular vesicles in immuno-oncology: From target specific isolations to immunomodulation
Extracellular vesicles (EVs) have been hypothesized to incorporate a variety of crucial roles
ranging from intercellular communication to tumor pathogenesis to cancer immunotherapy …
ranging from intercellular communication to tumor pathogenesis to cancer immunotherapy …