miRNAs as therapeutic targets in inflammatory disease
Q Lu, R Wu, M Zhao, A Garcia-Gomez… - Trends in pharmacological …, 2019 - cell.com
In the past decade, we have witnessed considerable developments in understanding the
roles and functions of miRNAs. In parallel, the identification of alterations in miRNA …
roles and functions of miRNAs. In parallel, the identification of alterations in miRNA …
The role of microRNA in psoriasis: A review
X Jiang, R Shi, R Ma, X Tang, Y Gong… - Experimental …, 2023 - Wiley Online Library
Psoriasis is a chronic immune‐mediated inflammatory skin disease that involves a complex
interplay between infiltrated immune cells and keratinocytes. Great progress has been made …
interplay between infiltrated immune cells and keratinocytes. Great progress has been made …
[HTML][HTML] Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype
L Terlecki-Zaniewicz, I Lämmermann, J Latreille… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Loss of functionality during aging of cells and organisms is caused and accompanied by
altered cell-to-cell communication and signalling. One factor thereby is the chronic …
altered cell-to-cell communication and signalling. One factor thereby is the chronic …
BMSC-derived exosomes carrying microRNA-122-5p promote proliferation of osteoblasts in osteonecrosis of the femoral head
W Liao, YU Ning, HJ Xu, WZ Zou, J Hu, XZ Liu… - Clinical …, 2019 - portlandpress.com
Mesenchymal stem cells (MSCs) with multipotential differentiation capacity can differentiate
into bone cells under specific conditions and can be used to treat osteonecrosis (ON) of the …
into bone cells under specific conditions and can be used to treat osteonecrosis (ON) of the …
[HTML][HTML] Adipose mesenchymal stromal cell-derived exosomes carrying MiR-122-5p antagonize the inhibitory effect of dihydrotestosterone on hair follicles by targeting …
Y Liang, X Tang, X Zhang, C Cao, M Yu… - International Journal of …, 2023 - mdpi.com
Androgenic alopecia (AGA) is the most common type of hair loss, where local high
concentrations of dihydrotestosterone (DHT) in the scalp cause progressive shrinkage of the …
concentrations of dihydrotestosterone (DHT) in the scalp cause progressive shrinkage of the …
[HTML][HTML] MicroRNAs in several cutaneous autoimmune diseases: Psoriasis, cutaneous lupus erythematosus and atopic dermatitis
S Domingo, C Solé, T Moliné, B Ferrer… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) are endogenous small non-coding RNA molecules that regulate the
gene expression at a post-transcriptional level and participate in maintaining the correct cell …
gene expression at a post-transcriptional level and participate in maintaining the correct cell …
Insights into interplay of immunopathophysiological events and molecular mechanistic cascades in psoriasis and its associated comorbidities
Psoriasis is an inflammatory skin disease with complex pathogenesis and multiple
etiological factors. Besides the essential role of autoreactive T cells and constellation of …
etiological factors. Besides the essential role of autoreactive T cells and constellation of …
[HTML][HTML] miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and …
F Zhou, W Chen, Y Cui, B Liu, Q Yuan, Z Li… - Aging (Albany NY …, 2020 - ncbi.nlm.nih.gov
Epigenetic regulators of human spermatogonia stem cells (SSCs) remain largely unknown.
We found that miRNA-122-5p was upregulated in human spermatogonia from obstructive …
We found that miRNA-122-5p was upregulated in human spermatogonia from obstructive …
The lncRNA H19/miR‐766‐3p/S1PR3 Axis Contributes to the Hyperproliferation of Keratinocytes and Skin Inflammation in Psoriasis via the AKT/mTOR Pathway
Y He, X Yin, J Yan, X Li, Q Sun - Mediators of Inflammation, 2021 - Wiley Online Library
Background. The pathogenesis of long noncoding RNAs (lncRNAs) and microRNAs
(miRNAs) are well studied in psoriasis. However, little is known about how specific lncRNAs …
(miRNAs) are well studied in psoriasis. However, little is known about how specific lncRNAs …
Downregulation of miR‐145‐5p contributes to hyperproliferation of keratinocytes and skin inflammation in psoriasis
JJ Yan, M Qiao, RH Li, XT Zhao… - British Journal of …, 2019 - academic.oup.com
Background The extensive involvement of microRNAs (miRNAs) in the pathogenesis of
psoriasis is well documented. However, little is known about the contribution of specific …
psoriasis is well documented. However, little is known about the contribution of specific …