Deep brain stimulation for treatment-resistant depression: follow-up after 3 to 6 years
SH Kennedy, P Giacobbe, SJ Rizvi… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: A prevalence of at least 30% for treatment-resistant depression has prompted the
investigation of alternative treatment strategies. Deep brain stimulation (DBS) is a promising …
investigation of alternative treatment strategies. Deep brain stimulation (DBS) is a promising …
Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents
Background Very few studies have been performed to understand the underlying neural
substrates of adolescent major depressive disorder (MDD). Studies in depressed adults …
substrates of adolescent major depressive disorder (MDD). Studies in depressed adults …
The subcallosal cingulate gyrus in the context of major depression
The subcallosal cingulate gyrus (SCG), including Brodmann area 25 and parts of 24 and 32,
is the portion of the cingulum that lies ventral to the corpus callosum. It constitutes an …
is the portion of the cingulum that lies ventral to the corpus callosum. It constitutes an …
Where in the brain is depression?
Major depressive disorder is a serious medical illness which is responsible for considerable
morbidity and disability. Despite decades of research, the neural basis for depression is still …
morbidity and disability. Despite decades of research, the neural basis for depression is still …
Antidepressant actions of histone deacetylase inhibitors
HE Covington, I Maze, QC LaPlant… - Journal of …, 2009 - Soc Neuroscience
Persistent symptoms of depression suggest the involvement of stable molecular adaptations
in brain, which may be reflected at the level of chromatin remodeling. We find that chronic …
in brain, which may be reflected at the level of chromatin remodeling. We find that chronic …
Long-term outcomes of subcallosal cingulate deep brain stimulation for treatment-resistant depression
AL Crowell, P Riva-Posse… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Deep brain stimulation of the subcallosal cingulate (SCC DBS) has been studied
as a potential treatment for severe and refractory major depressive disorder since 2005. The …
as a potential treatment for severe and refractory major depressive disorder since 2005. The …
Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient
Discussion. The DBS procedure resulted in a sustained full remission of depressive
symptoms in a patient who was therapyresistant to all standard treatments for at least 9 …
symptoms in a patient who was therapyresistant to all standard treatments for at least 9 …
Stuck in a rut: rethinking depression and its treatment
PE Holtzheimer, HS Mayberg - Trends in neurosciences, 2011 - cell.com
The current definition of major depressive disorder (MDD) emerged from efforts to create
reliable diagnostic criteria for clinical and research use. However, despite decades of …
reliable diagnostic criteria for clinical and research use. However, despite decades of …
[HTML][HTML] Deep brain stimulation for psychiatric disorders: From focal brain targets to cognitive networks
CRP Sullivan, S Olsen, AS Widge - Neuroimage, 2021 - Elsevier
Deep brain stimulation (DBS) is a promising intervention for treatment-resistant psychiatric
disorders, particularly major depressive disorder (MDD) and obsessive-compulsive disorder …
disorders, particularly major depressive disorder (MDD) and obsessive-compulsive disorder …
[HTML][HTML] Deep brain stimulation targets for treating depression
D Drobisz, A Damborská - Behavioural brain research, 2019 - Elsevier
Deep brain stimulation (DBS) is a new therapeutic approach for treatment-resistant
depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD …
depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD …