For the block-and-lock cure strategy to succeed more investigation into the transcriptional
and epigenetic regulation of HIV-1 gene expression is necessary to design optimal latency …

Lysine crotonylation is a newly identified posttranslational modification that is different from
the widely studied lysine acetylation in structure and function. In the last dozen years, great …

The formation of the human gut microbiome initiates in utero, and its maturation is
established during the first 2–3 years of life. Numerous factors alter the composition of the …

Histone post-translational modifications are reversible epigenetic mechanisms that regulate
chromatin structure and gene transcription. In recent years, in addition to the well …

Stem cells represent the regenerative capacity of our bodies; hence, it is essential for these
cells to interact with the intrinsic and extrinsic environments, including nutritional …

Recent advances in the understanding of the multilayered biology of the human genome
have revived interest in the role of epigenetic variations, particularly histone modifications …

Epigenetic modification is a fundamental biological process in living organisms, which has
significant impact on health and behavior. Metabolism refers to a set of life-sustaining …

Change is a constant in life, and being able to respond to change is essential for every living
being. This may be especially true for sessile long-lived perennials with a complex life cycle …

From generation of germ cells, fertilization, and throughout early mammalian embryonic
development, the chromatin undergoes significant alterations to enable precise regulation of …

Aging, shifting demographics, and lifestyle changes are some of the underlying factors
contributing to an increase in the incidence and prevalence of age-related disorders. Brain …