Advances in copper complexes as anticancer agents
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
[PDF][PDF] Experimental techniques employed in the study of metal complexes-DNA–interactions
The present paper is an overlook on metal complexes-DNA interactions, their classification
and the experimental techniques employed to study them. The deoxyribonucleic acid (DNA) …
and the experimental techniques employed to study them. The deoxyribonucleic acid (DNA) …
Copper (II) complexes with naringenin and hesperetin: cytotoxic activity against A 549 human lung adenocarcinoma cells and investigation on the mode of action
LV Tamayo, LR Gouvea, AC Sousa, RM Albuquerque… - Biometals, 2016 - Springer
Abstract Copper (II) complexes [Cu (H 2 O) 2 (L1)(phen)](ClO 4)(1) and [Cu (H 2
O)(L2)(phen)](ClO 4)(2)(HL1= naringenin; HL2= hesperetin) were obtained, in which an …
O)(L2)(phen)](ClO 4)(2)(HL1= naringenin; HL2= hesperetin) were obtained, in which an …
Novel mitochondria targeted copper (II) complexes of ferrocenyl terpyridine and anticancer active 8-hydroxyquinolines showing remarkable cytotoxicity, DNA and …
B Deka, T Sarkar, S Banerjee, A Kumar… - Dalton …, 2017 - pubs.rsc.org
Metal complexes with organelle specificity and potent but selective cytotoxicity are highly
desirable. In this work, we report the synthesis, characterization and cytotoxicity of six novel …
desirable. In this work, we report the synthesis, characterization and cytotoxicity of six novel …
A mitochondrion-targeting copper complex exhibits potent cytotoxicity against cisplatin-resistant tumor cells through multiple mechanisms of action
W Zhou, X Wang, M Hu, C Zhu, Z Guo - Chemical Science, 2014 - pubs.rsc.org
Copper complexes are potential anticancer drugs by virtue of their available redox
properties and low toxicity. In this study, a copper (II) complex,[Cu (ttpy-tpp) Br2] Br …
properties and low toxicity. In this study, a copper (II) complex,[Cu (ttpy-tpp) Br2] Br …
DNA interactions and biocidal activity of metal complexes of benzothiazole Schiff bases: Synthesis, characterization and validation
N Vamsikrishna, MP Kumar, G Ramesh, N Ganji… - Journal of Chemical …, 2017 - Springer
Binary complexes of Cu (II), Ni (II) and Co (II) were synthesized using two novel Schiff bases
L _ 1 L 1= 2-(-(benzothiazol-6-ylimino) methyl)-4-chlorophenol (BTEMCP), L _ 2 L 2= 2 …
L _ 1 L 1= 2-(-(benzothiazol-6-ylimino) methyl)-4-chlorophenol (BTEMCP), L _ 2 L 2= 2 …
Synthesis, characterization, DNA binding, cleavage activity, cytotoxicity and molecular docking of new nano water-soluble [M (5-CH 2 PPh 3-3, 4-salpyr)](ClO 4) 2 (M …
Z Mandegani, Z Asadi, M Asadi… - Dalton …, 2016 - pubs.rsc.org
Some new water soluble complexes [N, N′-bis {5-[(triphenyl phosphonium chloride)-
methyl] salicylidine}-3, 4-diaminopyridine] M (II), which are formulated as nano-[Zn (5 …
methyl] salicylidine}-3, 4-diaminopyridine] M (II), which are formulated as nano-[Zn (5 …
Targeting of DNA molecules, BSA/c-Met tyrosine kinase receptors and anti-proliferative activity of bis (terpyridine) copper (II) complexes
A series of homoleptic bis (terpyridine) copper (II) complexes of the type [Cu (L1–5) 2] Cl2 (1–
5), where L1–5= 4′-(4-substituted)-2, 2′: 6′, 2′′-terpyridines, have been synthesized …
5), where L1–5= 4′-(4-substituted)-2, 2′: 6′, 2′′-terpyridines, have been synthesized …
Synthesis, DNA interaction and anticancer activity of copper (II) complexes with 4′-phenyl-2, 2′: 6′, 2 ″-terpyridine derivatives
JW Liang, Y Wang, KJ Du, GY Li, RL Guan, LN Ji… - Journal of Inorganic …, 2014 - Elsevier
Three novel copper (II) complexes CuL 1 Cl 2 (1)(L 1= 4′-(3-methoxyphenyl)-2, 2′: 6′-2
″-terpyridine), CuL 2 Cl 2 (2)(L 2= 4′-(4-methoxyphenyl)-2, 2′: 6′-2 ″-terpyridine) and …
″-terpyridine), CuL 2 Cl 2 (2)(L 2= 4′-(4-methoxyphenyl)-2, 2′: 6′-2 ″-terpyridine) and …
[HTML][HTML] Synthesis, structure information, DNA/BSA binding affinity and in vitro cytotoxic studies of mixed ligand copper (II) complexes containing a phenylalanine …
Abstract Binary [Cu (PAIC)(H 2 O) 2]· H 2 O (1) and mixed ligand [Cu (PAIC)(L)]· 2H 2 O
complexes, where PAIC= phenylalanine imidazole carboxylic acid, L= diimine coligands [2 …
complexes, where PAIC= phenylalanine imidazole carboxylic acid, L= diimine coligands [2 …