Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

The bias towards excluding women from exercise science research is often due to the
assumption that cyclical fluctuations in reproductive hormones influence resistance exercise …

Insulin resistance and muscle mass loss often coincide in individuals with type 2 diabetes.
Most patients with type 2 diabetes are overweight, and it is well established that obesity and …

Maintenance of skeletal muscle mass throughout the life course is key for the regulation of
health, with physical activity a critical component of this, in part, due to its influence upon key …

Sarcopenia is defined as the combined loss of skeletal muscle strength, function, and/or
mass with aging. This degenerative loss of muscle mass is associated with poor quality of …

Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health
and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity …

Highlights•Changes in muscle mass and strength are mediated by the FITT
principles.•Frequency: more sessions per week may mediate (volume-dependent) muscle …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

It is universally accepted that resistance training promotes increases in muscle strength and
hypertrophy in younger and older populations. Although less investigated, studies largely …

Background The andropause is associated with declines in serum testosterone (T), loss of
muscle mass (sarcopenia), and frailty. Two major interventions purported to offset …