The neuropilins (Nrps) are multifunctional proteins involved in development, immunity and
cancer. Neuropilin-1 (Nrp1), or its homologue neuropilin-2 (Nrp2), are coreceptors that …

The semaphorins and their receptors, the neuropilins and the plexins, were originally
characterized as constituents of the complex regulatory system responsible for the guidance …

BACKGROUND Pain remains the cardinal symptom of endometriosis. However, to date, the
underlying mechanisms are still only poorly understood. Increasing evidence points towards …

Abstract Neuropilin-1 (Nrp1) is a multifunctional protein, identified principally as a receptor
for the class 3 semaphorins and members of the vascular endothelial growth factor (VEGF) …

From the original concepts that tumors require a vascular supply to grow and that blocking
angiogenesis could suppress tumor growth, the oncology field has witnessed clinical …

Neuropilin (NRP) 1 is a receptor for the vascular endothelial growth factor (VEGF)-A and is
essential for normal angiogenesis. Previous in vitro experiments identified NRP1 …

Abstract Neuropilin (Nrp)-1 and Nrp-2 are multifunctional proteins frequently expressed by
cancer cells and contribute to tumor progression by mechanisms that are not well …

Ovarian cancer is a significant malignancy for women in the Western world, and its death
rate has remained unchanged over the past 50 years, leaving room for proper …

Background—New revascularization therapies are urgently needed for patients with severe
coronary heart disease who lack conventional treatment options. Methods and Results—We …

The formation of the cardiovasculature, consisting of both the heart and blood vessels, is a
critical step in embryonic development and relies on three processes termed …