Nature is a rich source of biologically active novel compounds. Sixty years ago, the plant
hormones cytokinins were first discovered. These play a major role in cell division and cell …

Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also
been traditionally used for medicinal purposes. Carob contains many nutrients and active …

Metastatic breast cancer is an incurable form of breast cancer that exhibits high levels of
epithelial-mesenchymal transition (EMT) markers. Angiotensin II has been linked to various …

The nephrotoxicity of cisplatin (CIS) is a significant complication that challenges its clinical
applicability. The epithelial to mesenchymal transition (EMT) may be included in the …

Idiopathic pulmonary fibrosis is a progressive, irreversible lung disease that leads to
respiratory failure and death. Vincamine is an indole alkaloid obtained from the leaves of …

Pantoprazole has an antioxidant function against reactive oxygen species (ROS).
Vincamine, a herbal candidate, is an indole alkaloid of clinical use against brain sclerosis …

Aims Sepsis is a severe inflammatory response to infection with an incidence rate exceeding
48 million cases and 11 million sepsis-related deaths yearly. Furthermore, sepsis remains …

Renal ischemia/reperfusion (IR) injury is characterized by an unexpected impairment of
blood flow to the kidney. Azilsartan is an angiotensin receptor blocker that is approved for …

Inflammation is a critical defensive mechanism mainly arising due to the production of
prostaglandins via cyclooxygenase enzymes. This study aimed to examine the anti …

Abstract Glycogen synthase kinase-3 (GSK-3) is a protein kinase that can phosphorylate
over a hundred substrates and regulate cell differentiation, proliferation, and death …