[HTML][HTML] LGALS3BP in microglia promotes retinal angiogenesis through PI3K/AKT pathway during hypoxia

C Zhao, Y Liu, J Meng, X Wang, X Liu… - … & Visual Science, 2022 - tvst.arvojournals.org
Purpose: Retinal microglia promote angiogenesis and vasculopathy in oxygen-induced
retinopathy (OIR); however, its specific molecular mechanism in the formation of retinal …

Exosomes from human placenta choriodecidual membrane-derived mesenchymal stem cells mitigate endoplasmic reticulum stress, inflammation, and lung injury in …

MD Chiang, CY Chang, HJ Shih, VL Le, YH Huang… - Antioxidants, 2022 - mdpi.com
Endoplasmic reticulum (ER) stress mediates the effects of obesity on aggravating sepsis-
induced lung injury. We investigated whether exosomes from human placenta …

Human retinal progenitor cells derived small extracellular vesicles delay retinal degeneration: A paradigm for cell-free therapy

M Chen, C Ren, B Ren, Y Fang, Q Li, Y Zeng… - Frontiers in …, 2021 - frontiersin.org
Retinal degeneration is a leading cause of irreversible vision impairment and blindness
worldwide. Previous studies indicate that subretinal injection of human retinal progenitor …

LncRNAs in cardiomyocyte maturation: new window for cardiac regenerative medicine

M Kay, BM Soltani - Non-coding RNA, 2021 - mdpi.com
Cardiomyocyte (CM) maturation, which is characterized by structural, functional, and
metabolic specializations, is the last phase of CM development that prepares the cells for …

Long non-coding RNA TTTY15 silencing inhibits gastric cancer progression by sponging microRNA-98-5p to down-regulate cyclin D2 expression

X Wen, W Han, C Liu - Bioengineered, 2022 - Taylor & Francis
Gastric cancer is the most common malignant tumor in the digestive system. However, the
detection rate of early gastric cancer is low, resulting in delayed prognosis and poor …

Wuzi-Yanzong prescription alleviates spermatogenesis disorder induced by heat stress dependent on Akt, NF-κB signaling pathway

SQ Hu, DL Liu, CR Li, YH Xu, K Hu, LD Cui, J Guo - Scientific Reports, 2021 - nature.com
Akt and nuclear factor kappa B (NF-κB) signaling pathways are involved in germ cell
apoptosis and inflammation after testicular heat stress (THS). We observed that after THS …

Identification of biomarkers associated with metabolic cardiovascular disease using mRNA-SNP-miRNA regulatory network analysis

Z Fan, W Peng, Z Wang, L Zhang, K Liu - BMC Cardiovascular Disorders, 2021 - Springer
Background CVD is the leading cause of death in T2DM patients. However, few biomarkers
have been identified to detect and diagnose CVD in the early stage of T2DM. The aim of our …

Let-7i-5p mediates the therapeutic effects of exosomes from human placenta choriodecidual membrane-derived mesenchymal stem cells on mitigating endotoxin …

CY Chang, KY Chen, HJ Shih, M Chiang, IT Huang… - Pharmaceuticals, 2021 - mdpi.com
Obesity complicates sepsis and increases the mortality of sepsis. We examined the effects of
exosomes (from human placenta choriodecidual membrane-derived mesenchymal stem …

Comparative Phosphoproteomics Reveals a Role for AMPK in Hypoxia Signaling in Testes of Oriental River Prawn (Macrobrachium nipponense)

S Sun, Q Zhao, C Xue, C Zheng - Journal of Proteome Research, 2021 - ACS Publications
Hypoxia is one of the major stresses in aquaculture animals. Recently, we reported that
hypoxia disrupts the endocrine system and inhibits testicular function of oriental river prawns …

Analyses of Long Noncoding RNA and mRNA Profiles in Subjects with the Phlegm‐Dampness Constitution

L Dong, Y Zheng, D Liu, F He, K Lee… - BioMed Research …, 2021 - Wiley Online Library
Background. Constitution in traditional Chinese medicine (TCM) plays a key role in the
genesis, development, and prognosis of diseases. Phlegm‐dampness constitution (PDC) is …