Micro-and nano-devices for electrochemical sensing

F Mariani, I Gualandi, W Schuhmann, E Scavetta - Microchimica Acta, 2022 - Springer
Electrode miniaturization has profoundly revolutionized the field of electrochemical sensing,
opening up unprecedented opportunities for probing biological events with a high spatial …

High throughput toxicity screening and intracellular detection of nanomaterials

AR Collins, B Annangi, L Rubio… - Wiley …, 2017 - Wiley Online Library
With the growing numbers of nanomaterials (NMs), there is a great demand for rapid and
reliable ways of testing NM safety—preferably using in vitro approaches, to avoid the ethical …

Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis

A Jelinek, L Heyder, M Daude, M Plessner… - Free Radical Biology …, 2018 - Elsevier
Research into oxidative cell death is producing exciting new mechanisms, such as
ferroptosis, in the neuropathologies of cerebral ischemia and hemorrhagic brain insults …

[HTML][HTML] BID links ferroptosis to mitochondrial cell death pathways

S Neitemeier, A Jelinek, V Laino, L Hoffmann… - Redox biology, 2017 - Elsevier
Ferroptosis has been defined as an oxidative and iron-dependent pathway of regulated cell
death that is distinct from caspase-dependent apoptosis and established pathways of death …

Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis

A Marmolejo-Garza, IE Krabbendam, MDA Luu… - Cell Death & …, 2023 - nature.com
Ferroptosis is an iron-and reactive oxygen species (ROS)-dependent form of regulated cell
death, that has been implicated in Alzheimer's disease and Parkinson's disease. Inhibition of …

Mitochondrial reactive oxygen species formation determines ACSL4/LPCAT2-mediated ferroptosis

M Merkel, B Goebel, M Boll, A Adhikari, V Maurer… - Antioxidants, 2023 - mdpi.com
Ferroptosis is a form of oxidative cell death that is characterized by enhanced lipid
peroxidation and mitochondrial impairment. The enzymes acyl-CoA synthetase long-chain …

Glucose-regulated protein 75 determines ER–mitochondrial coupling and sensitivity to oxidative stress in neuronal cells

B Honrath, I Metz, N Bendridi, J Rieusset… - Cell death …, 2017 - nature.com
The crosstalk between different organelles allows for the exchange of proteins, lipids and
ions. Endoplasmic reticulum (ER) and mitochondria are physically linked and signal through …

Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction

AM Sabogal-Guáqueta, A Marmolejo-Garza… - Nature …, 2023 - nature.com
Metabolic reprogramming is a hallmark of the immune cells in response to inflammatory
stimuli. This metabolic process involves a switch from oxidative phosphorylation (OXPHOS) …

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities

BZ Schmidt, M Lehmann, S Gutbier, E Nembo… - Archives of …, 2017 - Springer
Neurotoxicity and developmental neurotoxicity are important issues of chemical hazard
assessment. Since the interpretation of animal data and their extrapolation to man is …

Real-time and non-invasive impedimetric monitoring of cell proliferation and chemosensitivity in a perfusion 3D cell culture microfluidic chip

KF Lei, MH Wu, CW Hsu, YD Chen - Biosensors and Bioelectronics, 2014 - Elsevier
A perfusion three-dimensional (3D) cell culture microfluidic chip has been developed for real-
time and non-invasive impedimetric monitoring of cell proliferation and chemosensitivity. In …