Objective A major side effect of cervical excision for high‐grade cervical intraepithelial
neoplasia (CIN) is premature birth. A non‐invasive treatment for reproductive age women is …

Toll-like receptors (TLRs) are crucial pattern recognition receptors in innate immunity that
are expressed in microglia, the resident macrophages of the brain. TLR2,-4, and-9 are …

Abstract mPEG-hexPLA micelles have shown their ability to improve delivery and cutaneous
bioavailability of a wide range of poorly water soluble and lipophilic molecules. Although …

Meningitis and meningoencephalitis caused by Escherichia coli are associated with high
rates of mortality. When an infection occurs, Toll-like receptors (TLRs) expressed by …

Synthetic oligonucleotides containing CpG motifs in specific sequence contexts have been
shown to induce potent immune responses. We have evaluated mucosal administration of …

Imiquimod (trade name Aldara™) is a small molecule of the imidazoquinoline family, a
group of nucleoside analogs that were first synthesized as potential antiviral agents. It has …

Warts are a common skin problem and are caused by infection with a virus. Warts are
currently mainly treated by therapies involving ablating tissue or interrupting cellular …

Imiquimod 5% cream (Aldara, Graceway Pharmaceuticals) is an immune response modifier
used for the topical treatment of anogenital warts in non-HIV-infected patients. Several …

Objective To investigate the efficacy of imiquimod in women with residual or recurrent
cervical intraepithelial neoplasia (rrCIN), compared with large loop excision of the …

Imiquimod cream is an immunomodulatory agent that has been approved by the US Food
and Drug Administration for use in the treatment of anogenital warts (condylomata …