The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Diverse mechanisms of antimicrobial activities of lactoferrins, lactoferricins, and other lactoferrin-derived peptides

Š Gruden, N Poklar Ulrih - International journal of molecular sciences, 2021 - mdpi.com
Lactoferrins are an iron-binding glycoprotein that have important protective roles in the
mammalian body through their numerous functions, which include antimicrobial, antitumor …

Dietary regulation of oxidative stress in chronic metabolic diseases

S Jiang, H Liu, C Li - Foods, 2021 - mdpi.com
Oxidative stress is a status of imbalance between oxidants and antioxidants, resulting in
molecular damage and interruption of redox signaling in an organism. Indeed, oxidative …

Insights into whey protein-based carriers for targeted delivery and controlled release of bioactive components

SR Falsafi, AC Karaca, L Deng, Y Wang, H Li… - Food …, 2022 - Elsevier
Whey proteins are promising biopolymers for designing bioactive delivery systems due to
their unique health-promoting attributes and the presence of multiple amino acid groups in …

[HTML][HTML] Evaluating the in vitro efficacy of bovine lactoferrin products against SARS-CoV-2 variants of concern

JW Wotring, R Fursmidt, L Ward, JZ Sexton - Journal of Dairy Science, 2022 - Elsevier
Bovine lactoferrin (bLF), a naturally occurring glycoprotein found in milk, has bioactive
characteristics against many microbes, viruses, and other pathogens. Bovine lactoferrin …

Whey proteins and peptides in health-promoting functions–A review

C Zhao, N Chen, TJ Ashaolu - International Dairy Journal, 2022 - Elsevier
Continuing studies show that whey components, notably proteins, have valuable nutritional
and techno-functional properties supporting their applications in foods and drinks …

Lactoferrin reduces the risk of respiratory tract infections: A meta-analysis of randomized controlled trials

AS Ali, SS Hasan, CS Kow, HA Merchant - Clinical Nutrition ESPEN, 2021 - Elsevier
Summary Background Lactoferrin (Lf) is one of the key immunomodulatory substances
found naturally in various body fluids, such as saliva, tears, and breast milk, and forms a vital …

An overview on in vitro and in vivo antiviral activity of lactoferrin: its efficacy against SARS-CoV-2 infection

L Rosa, A Cutone, MP Conte, E Campione, L Bianchi… - Biometals, 2023 - Springer
Beyond the absolute and indisputable relevance and efficacy of anti-SARS-CoV-2 vaccines,
the rapid transmission, the severity of infection, the absence of the protection on …

[HTML][HTML] Antiviral properties of whey proteins and their activity against SARS-CoV-2 infection

V Gallo, F Giansanti, A Arienzo, G Antonini - Journal of Functional Foods, 2022 - Elsevier
Native and chemically modified whey proteins and their peptide derivatives are
encountering the interest of nutraceutical and pharmaceutical industries, due to the …

SARS-CoV-2 infection dysregulates host iron (Fe)-redox homeostasis (Fe-RH): role of Fe-redox regulators, ferroptosis inhibitors, anticoagulants, and iron-chelators in …

SAG Naidu, RA Clemens, AS Naidu - Journal of Dietary …, 2023 - Taylor & Francis
Severe imbalance in iron metabolism among SARS-CoV-2 infected patients is prominent in
every symptomatic (mild, moderate to severe) clinical phase of COVID-19. Phase-I–Hypoxia …