Modulation of nitric oxide synthases by oxidized LDLs: role in vascular inflammation and atherosclerosis development

M Gliozzi, M Scicchitano, F Bosco, V Musolino… - International journal of …, 2019 - mdpi.com
The maintenance of physiological levels of nitric oxide (NO) produced by eNOS represents a
key element for vascular endothelial homeostasis. On the other hand, NO overproduction …

C‐type lectin receptors of the Dectin‐1 cluster: Physiological roles and involvement in disease

K Tone, MHT Stappers, JA Willment… - European Journal of …, 2019 - Wiley Online Library
C‐type lectin receptors (CLRs) are essential for multicellular existence, having diverse
functions ranging from embryonic development to immune function. One subgroup of CLRs …

High plasma levels of soluble lectin‐like oxidized low‐density lipoprotein receptor‐1 are associated with inflammation and cardiometabolic risk profiles in pediatric …

SE Stinson, AE Jonsson, MK Andersen… - Journal of the …, 2023 - Am Heart Assoc
Background Lectin‐like oxidized low‐density lipoprotein (ox‐LDL) receptor‐1 is a scavenger
receptor for oxidized low‐density lipoprotein. In adults, higher soluble lectin‐like ox‐LDL …

The role of immune system in atherosclerosis: Molecular mechanisms, controversies, and future possibilities

T Zhang, C Pang, M Xu, Q Zhao, Z Hu, X Jiang… - Human Immunology, 2024 - Elsevier
Numerous cardiovascular disorders have atherosclerosis as their pathological
underpinning. Numerous studies have demonstrated that, with the aid of pattern recognition …

Improvement of Endothelial Dysfunction of Berberine in Atherosclerotic Mice and Mechanism Exploring through TMT‐Based Proteomics

W Tan, Y Wang, K Wang, S Wang, J Liu… - Oxidative Medicine …, 2020 - Wiley Online Library
Atherosclerosis is a multifactorial vascular disease triggered by disordered lipid metabolism,
characterized by chronic inflammatory injury, and initiated by endothelial dysfunction …

LOX-1 activation by oxLDL induces AR and AR-V7 expression via NF-κB and STAT3 signaling pathways reducing enzalutamide cytotoxic effects

F Duprat, C Robles, MP Castillo, Y Rivas… - International Journal of …, 2023 - mdpi.com
The oxidized low-density lipoprotein receptor 1 (LOX-1) is one of the most important
receptors for modified LDLs, such as oxidated (oxLDL) and acetylated (acLDL) low-density …

Naringin reverses high‐cholesterol diet‐induced vascular dysfunction and oxidative stress in rats via regulating LOX‐1 and NADPH oxidase subunit expression

S Pengnet, S Prommaouan… - BioMed Research …, 2019 - Wiley Online Library
Hypercholesterolaemia is associated with oxidative stress and endothelial dysfunction and
leads to the development of atherosclerosis. Naringin exhibits cardiovascular protective and …

Influence of Periodontal Disease on cardiovascular markers in Diabetes Mellitus patients

JF Pedroso, Z Lotfollahi, G Albattarni… - Scientific reports, 2019 - nature.com
The objective of the present study was to establish if individuals with Diabetes Mellitus
(DM2) and periodontal diseases (gingivitis or periodontitis) presented an increase in the …

Green-banana biomass consumption by diabetic patients improves plasma low-density lipoprotein particle functionality

Z Lotfollahi, APQ Mello, ES Costa, CLP Oliveira… - Scientific reports, 2020 - nature.com
The aim of this study was to investigate the effects of 6-months consumption of green-
banana biomass on the LDL particle functionality in subjects with type 2 diabetes. Subjects …

Association of OLR1 gene polymorphisms with the risk of coronary artery disease: A systematic review and meta-analysis

P Salehipour, F Rezagholizadeh, M Mahdiannasser… - Heart & Lung, 2021 - Elsevier
Abstract Background Oxidized LDL receptor 1 (OLR1) encodes LOX-1, LOXIN, and OLR1D4
transcript variants. Up-regulation of LOX-1 and down-regulation of LOXIN have an essential …