[HTML][HTML] BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients
L Jin, E Chen, S Dong, Y Cai, X Zhang, Y Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The role of telomerase reverse transcriptase (TERT) gene promoter mutations in the
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …
Management of recurrent/persistent nodal disease in patients with differentiated thyroid cancer: a critical review of the risks and benefits of surgical intervention versus …
RP Tufano, G Clayman, KS Heller, WB Inabnet… - Thyroid, 2015 - liebertpub.com
Background: The primary goals of this interdisciplinary consensus statement are to define
the eligibility criteria for management of recurrent and persistent cervical nodal disease in …
the eligibility criteria for management of recurrent and persistent cervical nodal disease in …
Oncogenic Mutations in PI3K/AKT/mTOR Pathway Effectors Associate with Worse Prognosis in BRAFV600E-Driven Papillary Thyroid Cancer Patients
T Pappa, S Ahmadi, E Marqusee, HL Johnson… - Clinical Cancer …, 2021 - AACR
Purpose: The extent to which routine genomic sequencing can identify relevant secondary
genomic alterations among BRAFV600E-mutant papillary thyroid carcinoma (PTC) is …
genomic alterations among BRAFV600E-mutant papillary thyroid carcinoma (PTC) is …
Antitumor effects of anlotinib in thyroid cancer
There is no effective treatment for patients with poorly differentiated papillary thyroid cancer
or anaplastic thyroid cancer (ATC). Anlotinib, a multi-kinase inhibitor, has already shown …
or anaplastic thyroid cancer (ATC). Anlotinib, a multi-kinase inhibitor, has already shown …
The prognostic value of tumor multifocality in clinical outcomes of papillary thyroid cancer
Context Multifocality is often treated as a risk factor for papillary thyroid cancer (PTC),
prompting aggressive treatments, but its prognostic value remains unestablished. Objective …
prompting aggressive treatments, but its prognostic value remains unestablished. Objective …
BRAFV600E in Papillary Thyroid Carcinoma Is Associated with Increased Programmed Death Ligand 1 Expression and Suppressive Immune Cell Infiltration
TE Angell, MG Lechner, JK Jang, AJ Correa… - Thyroid, 2014 - liebertpub.com
Background: There remain a small number of patients with papillary thyroid cancer (PTC)
who suffer recurrence, metastases, or death. While mutation of the BRAF gene …
who suffer recurrence, metastases, or death. While mutation of the BRAF gene …
BRAFV600E Is Correlated with Recurrence of Papillary Thyroid Microcarcinoma: A Systematic Review, Multi-Institutional Primary Data Analysis, and Meta-Analysis
Background: Given the increasing incidence of papillary thyroid carcinoma despite stable
disease-specific mortality rates, the potential for the disease to reoccur is a key outcome to …
disease-specific mortality rates, the potential for the disease to reoccur is a key outcome to …
Relationship between BRAF V600E and clinical features in papillary thyroid carcinoma
C Yan, M Huang, X Li, T Wang… - Endocrine connections, 2019 - ec.bioscientifica.com
Objective To investigate the mutant status of BRAF gene and analyze its relationship to
epidemiological risk factors and clinical outcomes among patients with papillary thyroid …
epidemiological risk factors and clinical outcomes among patients with papillary thyroid …
[HTML][HTML] Molecular alterations of coexisting thyroid papillary carcinoma and anaplastic carcinoma: identification of TERT mutation as an independent risk factor for …
Thyroid papillary carcinoma is the most common endocrine neoplasm and generally carries
a favorable prognosis. However, a small subset of papillary carcinomas transforms into …
a favorable prognosis. However, a small subset of papillary carcinomas transforms into …
Centralized molecular testing for oncogenic gene mutations complements the local cytopathologic diagnosis of thyroid nodules
S Beaudenon-Huibregtse, EK Alexander, RB Guttler… - Thyroid, 2014 - liebertpub.com
Background: Molecular testing for oncogenic gene mutations and chromosomal
rearrangements plays a growing role in the optimal management of thyroid nodules, yet …
rearrangements plays a growing role in the optimal management of thyroid nodules, yet …