TERT Promoter Mutations in Thyroid Cancer

AS Alzahrani, R Alsaadi, AK Murugan, BB Sadiq - Hormones and Cancer, 2016 - Springer
Two mutations (C228T and C250T) in the promoter region of the telomerase reverse
transcriptase (TERT) have recently been described in different types of cancer including …

Distinct molecular subtypes of papillary thyroid carcinoma and gene signature with diagnostic capability

S Hong, Y Xie, Z Cheng, J Li, W He, Z Guo, Q Zhang… - Oncogene, 2022 - nature.com
Papillary thyroid carcinoma (PTC) is heterogeneous and its molecular characteristics remain
elusive. We integrated transcriptomic sequencing, genomic analysis and clinicopathologic …

[HTML][HTML] Signaling pathways in thyroid cancer and their therapeutic implications

S Jin, O Borkhuu, W Bao, YT Yang - Journal of clinical medicine …, 2016 - ncbi.nlm.nih.gov
Thyroid cancer is a common malignancy of endocrine system, and has now become the
fastest increasing cancer among all the malignancies. The development, progression …

Controversies in the management of low-risk differentiated thyroid cancer

MR Haymart, NH Esfandiari, MT Stang… - Endocrine …, 2017 - academic.oup.com
Controversy exists over optimal management of low-risk differentiated thyroid cancer. This
controversy occurs in all aspects of management, including surgery, use of radioactive …

Rising incidence and incidence-based mortality of thyroid cancer in California, 2000-2017

KL Yan, S Li, CH Tseng, J Kim… - The Journal of …, 2020 - academic.oup.com
Context The increased incidence of thyroid cancer globally over the past several decades is
principally attributed to small, indolent papillary thyroid cancers. A possible concomitant …

ENDOCRINE TUMOURS: Genetic predictors of thyroid cancer outcome

C Tavares, M Melo… - European journal of …, 2016 - academic.oup.com
Genetic predictors of outcome are reviewed in the context of a disease–cancer–that can be
(too) simplistically described as a 'successful, invasive clone of our own tissues'. Context has …

A meta-analysis of prognostic roles of molecular markers in papillary thyroid carcinoma

HG Vuong, UNP Duong, AMA Altibi… - Endocrine …, 2017 - ec.bioscientifica.com
The prognostic role of molecular markers in papillary thyroid carcinoma (PTC) is a matter of
ongoing debate. The aim of our study is to investigate the impact of RAS, BRAF, TERT …

BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment

Y Huang, S Qu, G Zhu, F Wang, R Liu… - JNCI: Journal of the …, 2018 - academic.oup.com
Background Precise risk stratification-based treatment of solitary intrathyroidal papillary
thyroid cancer (SI-PTC) that is larger than 1.0 cm and 4.0 cm or less is undefined. Methods A …

[HTML][HTML] BRAF V600E confers male sex disease-specific mortality risk in patients with papillary thyroid cancer

F Wang, S Zhao, X Shen, G Zhu, R Liu… - Journal of clinical …, 2018 - ncbi.nlm.nih.gov
BRAF V600E Confers Male Sex Disease-Specific Mortality Risk in Patients With Papillary
Thyroid Cancer - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Influence of nomenclature changes on trends in papillary thyroid cancer incidence in the United States, 2000 to 2017

CM Kitahara, JA Sosa, MS Shiels - The Journal of Clinical …, 2020 - academic.oup.com
Context US papillary thyroid carcinoma (PTC) incidence recently declined for the first time in
decades, for reasons that remain unclear. Objective This work aims to evaluate PTC …