Petroleum hydrocarbon compounds are persistent organic pollutants, which can cause
permanent damage to ecosystems due to their biomagnification. Bioremediation of oil is …

The versatility of RNA in sensing and interacting with small molecules, proteins and other
nucleic acids while encoding genetic instructions for protein translation makes it a powerful …

Non-model microorganisms often possess complex phenotypes that could be important for
the future of biofuel and chemical production. They have received significant interest the last …

Cell-free systems that display complex functions without using living cells are emerging as
new platforms to test our understanding of biological systems as well as for practical …

RNA structure regulates bacterial gene expression by several distinct mechanisms via
environmental and cellular stimuli, one of which is temperature. While some genome-wide …

RNA can self‐fold into complex structures that can serve as major biological regulators in
protein synthesis and in catalysis. Due to the abundance of structural primitives and …

The detection of chemicals using natural allosteric transcription factors is a powerful strategy
for point-of-use molecular sensing, particularly using fieldable cell-free gene expression …

Phenylpropanoids comprise a large class of specialized plant metabolites with many
important applications, including pharmaceuticals, food nutrients, colorants, fragrances, and …

Optimising the function of a protein of length N amino acids by directed evolution involves
navigating a 'search space'of possible sequences of some 20 N. Optimising the expression …

The sequences of the 5′ untranslated regions (5′-UTRs) of mRNA alter gene expression
across domains of life. Transcriptional modulators can be easily assayed through …