Role of oxidative stress in Alzheimer's disease

WJ Huang, XIA Zhang, WW Chen - Biomedical reports, 2016 - spandidos-publications.com
Alzheimer's disease (AD) is the most common cause of disability in individuals aged> 65
years worldwide. AD is characterized by the abnormal deposition of amyloid β (Aβ) peptide …

Oxidative toxicity in diabetes and Alzheimer's disease: mechanisms behind ROS/RNS generation

W Ahmad, B Ijaz, K Shabbiri, F Ahmed… - Journal of biomedical …, 2017 - Springer
Reactive oxidative species (ROS) toxicity remains an undisputed cause and link between
Alzheimer's disease (AD) and Type-2 Diabetes Mellitus (T2DM). Patients with both AD and …

Natural product for the treatment of Alzheimer's disease

TT Bui, TH Nguyen - Journal of basic and clinical physiology and …, 2017 - degruyter.com
Alzheimer's disease (AD) is related to increasing age. It is mainly characterized by
progressive neurodegenerative disease, which damages memory and cognitive function …

JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer's and various neurodegenerative abnormalities

S Mehan, H Meena, D Sharma, R Sankhla - Journal of Molecular …, 2011 - Springer
The c-Jun N-terminal kinase (JNKs), also known as stress-activated protein kinase (SAPK),
is one such family of multifunctional-signaling molecules, activated in response to wide …

Free radical biology in neurological manifestations: mechanisms to therapeutics interventions

R Tripathi, R Gupta, M Sahu, D Srivastava… - … Science and Pollution …, 2021 - Springer
Recent advancements and growing attention about free radicals (ROS) and redox signaling
enable the scientific fraternity to consider their involvement in the pathophysiology of …

Redox nanoparticles: synthesis, properties and perspectives of use for treatment of neurodegenerative diseases

I Sadowska-Bartosz, G Bartosz - Journal of Nanobiotechnology, 2018 - Springer
Oxidative stress (OS) and nitrative stress (NS) accompany many diseases, including
Alzheimer's disease (AD) and Parkinson's disease (PD). Antioxidants have been proposed …

Recent advances in the treatment of neurodegenerative diseases based on GSH delivery systems

I Cacciatore, L Baldassarre, E Fornasari… - Oxidative medicine …, 2012 - Wiley Online Library
Neurodegenerative diseases, such as Parkinson′ s disease (PD) and Alzheimer′ s
disease (AD), are a group of pathologies characterized by a progressive and specific loss of …

Clinical relevance of biomarkers, new therapeutic approaches, and role of post-translational modifications in the pathogenesis of Alzheimer's disease

I Mumtaz, MO Ayaz, MS Khan, U Manzoor… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that causes progressive loss of
cognitive functions like thinking, memory, reasoning, behavioral abilities, and social skills …

Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity

N Aydin, H Turkez, OO Tozlu, ME Arslan, M Yavuz… - Nanomaterials, 2022 - mdpi.com
Alzheimer's disease (AD) is considered as the most common neurodegenerative disease.
Extracellular amyloid beta (Aβ) deposition is a hallmark of AD. The options based on …

Molecular mechanisms highlighting the potential role of COVID-19 in the development of neurodegenerative diseases

B Rahmani, E Ghashghayi, M Zendehdel… - Physiology …, 2022 - akjournals.com
Abstract Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In addition to the pulmonary …