Cancer is a fatal disorder that affects people across the globe, yet existing therapeutics are
ineffective. The development of submicrometer transport for optimizing the biodistribution of …

Amyloidosis is a biophysical phenomenon of protein aggregation with biological and
pathogenic implications. Among the various strategies developed to date, nanomaterials …

Background The blood brain barrier (BBB) is the bottleneck of brain-targeted drug
development. Due to their physico-chemical properties, nanoparticles (NP) can cross the …

Here, prostaglandin D 2-glycerol ester (PGD 2-G) was selected to target neuroinflammation.
As PGD 2-G is reported to have a short plasmatic half-life, we propose to use lipid …

The submitted study reports the synthesis, crystal structure determination by the
spectroscopic and non-spectroscopic methods, comparison of computational and …

Polyphenol compounds, such as curcumin, rutin, rifampicin, can inhibit Aβ aggregation and
decrease reactive oxygen species (ROS), and have received much attention in recent years …

By incorporating appropriate drug (s) into lipid (biobased) nanocarriers, one obtains a
combination therapeutic for dementia treatment that targets certain cell-surface scavenger …

Due to the complexity of Alzheimer's disease, multiple cellular types need to be targeted
simultaneously in order for a given therapy to demonstrate any major effectiveness …

Alzheimer's Disease (AD) is one of the most challenging diseases faced by humankind. AD
is still not classified as curable because of the complex structure of pathologies underlying it …

Pregnancy is a delicate state, during which timely investigation of possible physiological
anomalies is essential to reduce the risk of maternal and fetal complications. Medical …