Background Computational scanning of peptide candidates that bind to a specific major
histocompatibility complex (MHC) can speed up the peptide-based vaccine development …

Immunoinformatics is a discipline that applies methods of computer science to study and
model the immune system. A fundamental question addressed by immunoinformatics is how …

Vaccine informatics is an emerging research area that focuses on development and
applications of bioinformatics methods that can be used to facilitate every aspect of the …

Killer cell immunoglobulin-like receptors (KIRs) are rapidly evolving species-specific natural
killer (NK) cell receptors associated with protection against multiple different human viral …

Binding of short antigenic peptides to major histocompatibility complex (MHC) molecules is
a core step in adaptive immune response. Precise identification of MHC-restricted peptides …

T cell immune responses are driven by the recognition of peptide antigens (T cell epitopes)
that are bound to major histocompatibility complex (MHC) molecules. T cell epitope …

Genome sequencing of humans and other organisms has led to the accumulation of huge
amounts of data, which include immunologically relevant data. A large volume of clinical …

Background Binding of peptides to Major Histocompatibility class II (MHC-II) molecules play
a central role in governing responses of the adaptive immune system. MHC-II molecules …

Understanding the mechanisms involved in the activation of an immune response is
essential to many fields in human health, including vaccine development and personalized …

Motivation: Immunological bioinformatics methods are applicable to a broad range of
scientific areas. The specifics of how and where they might be implemented have recently …