Understanding prediction systems for HLA-binding peptides and T-cell epitope identification

L You, P Zhang, M Bodén, V Brusic - … , PRIB 2007, Singapore, October 1-2 …, 2007 - Springer
Peptide binding to HLA molecules is a critical step in induction and regulation of T-cell
mediated immune responses. Because of combinatorial complexity of immune responses …

Enhancing Protein Interaction Prediction Using Deep Learning and Protein Language Models

N Hashemi - 2023 - search.proquest.com
Proteins are large macromolecules that play critical roles in many cellular activities in living
organisms. These include catalyzing metabolic reactions, mediating signal transduction …

[PDF][PDF] Immunoinformatics: how in silico methods are re-shaping the investigation of peptide immune specificity

LJK Wee, SJ Lim, LFP Ng… - Frontiers in Bioscience …, 2012 - article.imrpress.com
[Frontiers in Bioscience E4, 311-319, January 1, 2012] 311 Immunoinformatics: how in silico
methods are re-shaping the investiga Page 1 [Frontiers in Bioscience E4, 311-319, January 1 …

Genome to vaccinome: role of bioinformatics, immunoinformatics & comparative genomics

U Kulkarni-Kale, V Waman, S Raskar… - Current …, 2012 - ingentaconnect.com
Emerging and re-emerging viral infections are a threat to human health and a cause of
global concern. Several viral vaccines have been successfully developed using …

[HTML][HTML] Prediction of peptide binding to a major histocompatibility complex class I molecule based on docking simulation

T Ishikawa - Journal of computer-aided molecular design, 2016 - Springer
Binding between major histocompatibility complex (MHC) class I molecules and
immunogenic epitopes is one of the most important processes for cell-mediated immunity …

Modélisation du comportement des mousses solides à porosité ouverte: une approche micromécanique

M Laroussi - 2002 - pastel.hal.science
Le comportement des mousses solides est complexe. Selon le solide qui les constitue, elles
peuvent être élastiques, visco-élastiques, élasti-plastiques ou encore visco-élasto-plastique …

Modeling major histocompatibility complex binding by nonparametric averaging of multiple predictors and sequence encodings

JC Huang, N Jojic - Journal of immunological methods, 2011 - Elsevier
There has been considerable interest in statistical approaches that leverage the large
volumes of experimental data to predict the binding of Major Histocompatibility Complex …

HLA Moleküllerinde Peptit Ligandlarının Kompleks Stabilitesine Olan Etkisinin Araştırılması

A Bunsuz, O Serçinoğlu, P Özbek - Marmara Fen Bilimleri Dergisi, 2018 - dergipark.org.tr
Hücre yüzey glikoproteinleri olan Temel Doku Uygunluk Kompleks (MHC) molekülleri
yabancı antijenlere bağlanır ve onları uygun immün tanınma için antijen sunucu hücrelerin …

[HTML][HTML] Tat protein vaccination of cynomolgus macaques influences SHIV-89.6Pcy243 epitope variability

B Ridolfi, D Genovese, C Argentini, MT Maggiorella… - Virus genes, 2008 - Springer
In a previous study we showed that vaccination with the native Tat protein controlled virus
replication in five out of seven monkeys against challenge with the simian human …

Nonparametric combinatorial sequence models

FL Wauthier, MI Jordan, N Jojic - Journal of Computational Biology, 2011 - liebertpub.com
This work considers biological sequences that exhibit combinatorial structures in their
composition: groups of positions of the aligned sequences are “linked” and covary as one …