More than 40 million people are living with human immunodeficiency virus-1 (HIV-1). A
prophylactic vaccine inducing a 'sterilizing immunity'is desired to prevent further infections …

Major histocompatibility complex (MHC) molecules are heterodimeric cell surface
glycoproteins playing a novel role in the regulation of the adaptive immune response by …

The human leukocyte antigens (HLAs) can capture endogenous or exogenous peptides and
set up a cascade which results in immune activation to fight a pathogen or sometimes to …

Hepatitis C virus (HCV) is a major global pathogen that infects an estimated 170 million
people worldwide, and for which currently no vaccine is available. HCV is a highly diverse …

Background There are many viruses that result in persistent infections affecting millions of
people worldwide. Although our immune system deploys different strategies to eliminate …

Mammalian cells express a variety of host restriction factors to defend themselves against
pathogens. Viruses have evolved countermeasures to subvert their restriction and replicate …

Materials and Methods: We have developed a novel in silico epitope prediction method,
based on Hl. A crystal structure and a peptide docking simulation model, calculating the …

It has been shown repeatedly that infectious diseases in humans have strong associations
with the human leukocyte antigen system, but an understanding of the basis of these …

Major histocompatibility complexes (MHC) or human leukocyte antigens (HLAs) in human
are important elements of T cell-mediated immunity. They are cell surface glycoproteins …

Class-I major histocompatibility complex (MHC), peptide, and T-cell receptor (TCR) play an
essential role of adaptive immune responses. Many prediction servers are available for …