New lead structures in antifungal drug discovery

C Sheng, W Zhang - Current medicinal chemistry, 2011 - ingentaconnect.com
During the past two decades, the incidence of invasive fungal infections has been
increasing dramatically. Clinical available antifungal agents have several drawbacks such …

Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore

A Husain, SA Khan, F Iram, MA Iqbal, M Asif - European Journal of …, 2019 - Elsevier
Furanone, a five-membered heteroaromatic ring containing oxygen atom, is of immense
pharmaceutical importance. Presence of this nucleus in biologically active compounds of …

Palladium-Catalyzed α-Arylation of Zinc Enolates of Esters: Reaction Conditions and Substrate Scope

T Hama, S Ge, JF Hartwig - The Journal of organic chemistry, 2013 - ACS Publications
The intermolecular α-arylation of esters by palladium-catalyzed coupling of aryl bromides
with zinc enolates of esters is reported. Reactions of three different types of zinc enolates …

Facile and efficient synthesis of 3, 4, 5-substituted furan-2 (5H)-ones by using β-cyclodextrin as reusable catalyst

SN Murthy, B Madhav, AV Kumar, KR Rao… - Tetrahedron, 2009 - Elsevier
Facile and efficient synthesis of 3,4,5-substituted furan-2(5H)-ones by using β-cyclodextrin
as reusable catalyst - ScienceDirect Skip to main contentSkip to article Elsevier logo …

The palladium‐catalyzed aerobic kinetic resolution of secondary alcohols: reaction development, scope, and applications

DC Ebner, JT Bagdanoff, EM Ferreira… - … A European Journal, 2009 - Wiley Online Library
The first palladium‐catalyzed enantioselective oxidation of secondary alcohols has been
developed, utilizing the readily available diamine (−)‐sparteine as a chiral ligand and …

Efficient and eco‐friendly one‐pot synthesis of functionalized furan‐2‐one, pyrrol‐2‐one, and tetrahydropyridine using lemon juice as a biodegradable catalyst

MM Khan, S Khan, Saigal, SC Sahoo - ChemistrySelect, 2018 - Wiley Online Library
New and facile one‐pot approach for the syntheses of polysubstituted pyrrol‐2‐one, furan‐2‐
one and tetrahydropyridines (THPDs) from easily available starting materials using lemon …

[HTML][HTML] Preparation of 3, 4, 5-substituted furan-2 (5H)-ones using aluminum hydrogen sulfate as an efficient catalyst

MRM Shafiee, SS Mansoor, M Ghashang… - Comptes Rendus …, 2014 - Elsevier
Abstract Various derivatives of 3, 4, 5-substituted furan-2 (5H)-ones have been readily
prepared by using aluminum hydrogen sulfate [Al (HSO 4) 3] as an efficient catalyst in good …

Recent developments in γ-lactone synthesis

S Gil, M Parra, P Rodriguez… - Mini-Reviews in Organic …, 2009 - ingentaconnect.com
In recent years, several classes of biologically active molecules containing the γ-lactone
ring, pesticides, plant and fungal growth inhibitors, and antibiotics have been found. Thus …

Stereoselective construction of carbocycles and heterocycles via cascade reactions involving curcumins and nitroalkenes

N Ayyagari, D Jose, SM Mobin, INN Namboothiri - Tetrahedron Letters, 2011 - Elsevier
The reaction of curcumins with nitroalkenes has been investigated for the first time. Highly
functionalized cyclohexanones possessing three contiguous chiral centers with complete …

Isomerization of Olefins Triggered by Rhodium‐Catalyzed C H Bond Activation: Control of Endocyclic β‐Hydrogen Elimination

SYY Yip, C Aïssa - Angewandte Chemie, 2015 - Wiley Online Library
Five‐membered metallacycles are typically reluctant to undergo endocyclic β‐hydrogen
elimination. The rhodium‐catalyzed isomerization of 4‐pentenals into 3‐pentenals occurs …