Metabolic regulation of neutrophil functions in homeostasis and diseases
PO Leblanc, SG Bourgoin, PE Poubelle… - Journal of Leukocyte …, 2024 - academic.oup.com
Neutrophils are the most abundant leukocytes in humans and play a role in the innate
immune response by being the first cells attracted to the site of infection. While early studies …
immune response by being the first cells attracted to the site of infection. While early studies …
[HTML][HTML] The Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells
K Bishayee, SH Lee, YS Park - International Journal of Molecular …, 2023 - mdpi.com
A chemotherapeutic approach is crucial in malignancy management, which is often
challenging due to the development of chemoresistance. Over time, chemo-resistant cancer …
challenging due to the development of chemoresistance. Over time, chemo-resistant cancer …
[HTML][HTML] Warburg-associated acidification represses lactic fermentation independently of lactate, contribution from real-time NMR on cell-free systems
Z Daverio, M Kolkman, J Perrier, L Brunet… - Scientific Reports, 2023 - nature.com
Lactate accumulation and acidification in tumours are a cancer hallmark associated with the
Warburg effect. Lactic acidosis correlates with cancer malignancy, and the benefit it offers to …
Warburg effect. Lactic acidosis correlates with cancer malignancy, and the benefit it offers to …
[HTML][HTML] Synthesis and Biological Evaluation of Some New 3-Aryl-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones and 3-Aryl-2-(benzylthio)quinazolin-4(3H)-ones as …
NNE El-Sayed, TM Al-Otaibi, A Barakat… - Pharmaceuticals, 2023 - mdpi.com
Oxidative stress, COX-2, LDHA and hyperglycemia are interlinked contributing pathways in
the etiology, progression and metastasis of colon cancer. Additionally, dysregulated …
the etiology, progression and metastasis of colon cancer. Additionally, dysregulated …
[HTML][HTML] Severe lactic acidosis caused by thiamine deficiency in a child with relapsing acute lymphoblastic leukemia: a case report
Lactic acidosis is characterized by an excessive production of lactic acid or by its impaired
clearance. Thiamine deficiency is an uncommon cause of lactic acidosis, especially in …
clearance. Thiamine deficiency is an uncommon cause of lactic acidosis, especially in …
Histone lactylation bridges metabolic reprogramming and epigenetic rewiring in driving carcinogenesis: Oncometabolite fuels oncogenic transcription
Y Zhang, H Song, M Li, P Lu - Clinical and Translational …, 2024 - Wiley Online Library
Heightened lactate production in cancer cells has been linked to various cellular
mechanisms such as angiogenesis, hypoxia, macrophage polarisation and T‐cell …
mechanisms such as angiogenesis, hypoxia, macrophage polarisation and T‐cell …
[HTML][HTML] Lactic acidosis in a patient with cancer
M Oseguera, AA Yau - Clinical Medicine, 2023 - Elsevier
Lactic acidosis is commonly associated with tissue hypoperfusion and gives rise to concern
regarding hypoxia or underlying hypotension. In the cancer patient, especially one …
regarding hypoxia or underlying hypotension. In the cancer patient, especially one …
[HTML][HTML] Immune evasion by cancer stem cells ensures tumor initiation and failure of immunotherapy
S Chakraborty, S Mukherjee, U Basak… - Exploration of …, 2023 - explorationpub.com
Cancer stem cells (CSCs) are a small subpopulation of cells that drive the formation and
progression of tumors. However, during tumor initiation, how CSCs communicate with …
progression of tumors. However, during tumor initiation, how CSCs communicate with …
[HTML][HTML] N6-甲基腺苷阅读蛋白人类抗原R 对结直肠癌细胞的迁移, 侵袭和糖酵解的影响及其与磷酸果糖激酶1 的关系
王一丹， 王泊雅， 李璐， 张勇， 褚菲菲， 吴慧丽 - 实用临床医药杂志 - jcmp.yzu.edu.cn
N6-甲基腺苷阅读蛋白人类抗原R对结直肠癌细胞的迁移,侵袭和糖酵解的影响及其与磷酸果糖
激酶1的关系 高级检索 首页 期刊动态 1.公告栏 2.期刊要闻 3.学术动态 编委专家 1.主编风采 …
激酶1的关系 高级检索 首页 期刊动态 1.公告栏 2.期刊要闻 3.学术动态 编委专家 1.主编风采 …