Hypertensive disorders of pregnancy (HDP) remain one of the major causes of pregnancy-
related maternal and fetal morbidity and mortality worldwide. Affected women are also at …

The global prevalence of overweight and obesity in pregnancy is rising and this represents a
significant challenge for the management of pregnancy and delivery. Women who have a …

Preeclampsia (PE) is a multisystem disorder that typically affects 2%− 5% of pregnant
women and is one of the leading causes of maternal and perinatal morbidity and mortality …

Summary Pre-eclampsia affects 3–5% of pregnancies and is traditionally diagnosed by the
combined presentation of high blood pressure and proteinuria. New definitions also include …

Pregnancy-induced hypertension (PIH) complicates 6–10% of pregnancies. It is defined as
systolic blood pressure (SBP)> 140 mmHg and diastolic blood pressure (DBP)> 90 mmHg. It …

Maternal obesity is associated with placental lipotoxicity, oxidative stress, and inflammation,
where MAPK activity may play a central role. Accordingly, we have previously shown that …

Objective To summarize evidence from the literature on genetic and non‐genetic risk factors
associated with pre‐eclampsia (PE), assess the presence of statistical bias in the studies …

Regulatory T cells (Tregs) are a specialized subset of T lymphocytes that function as
suppressive immune cells and inhibit various elements of immune response in vitro and in …

Despite intensive investigation, we still cannot adequately predict, treat, or prevent
preeclampsia. We have gained awareness that preeclampsia is a syndrome not a disease …

Pre-eclampsia is increasingly recognized as more than an isolated disease of pregnancy.
Women who have had a pregnancy complicated by pre-eclampsia have a 4-fold increased …