Ophthalmic gels: Past, present and future

AA Al-Kinani, G Zidan, N Elsaid, A Seyfoddin… - Advanced drug delivery …, 2018 - Elsevier
Aqueous gels formulated using hydrophilic polymers (hydrogels) along with those based on
stimuli responsive polymers (in situ gelling or gel forming systems) continue to attract …

Principles of pharmacology in the eye

S Awwad, AHA Mohamed Ahmed… - British journal of …, 2017 - Wiley Online Library
The eye is a highly specialized organ that is subject to a huge range of pathology. Both local
and systemic disease may affect different anatomical regions of the eye. The least invasive …

Trends in formulation approaches for sustained drug delivery to the posterior segment of the eye

A Biswas, AD Choudhury, AC Bisen, S Agrawal… - AAPS …, 2023 - Springer
The eye, an intricate organ comprising physical and physiological barriers, poses a
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …

Evolution of nanotechnology in delivering drugs to eyes, skin and wounds via topical route

P Koppa Raghu, KK Bansal, P Thakor, V Bhavana… - Pharmaceuticals, 2020 - mdpi.com
The topical route is the most preferred one for administering drugs to eyes, skin and wounds
for reaching enhanced efficacy and to improve patient compliance. Topical administration of …

Delivery systems in ocular retinopathies: the promising future of intravitreal hydrogels as sustained-release scaffolds

D Rafael, M Guerrero, A Marican, D Arango… - Pharmaceutics, 2023 - mdpi.com
Slow-release delivery systems are needed to ensure long-term sustained treatments for
retinal diseases such as age-related macular degeneration and diabetic retinopathy, which …

Progress on ocular siRNA gene‐silencing therapy and drug delivery systems

J Jiang, X Zhang, Y Tang, S Li… - Fundamental & clinical …, 2021 - Wiley Online Library
Age‐related macular degeneration (AMD) and glaucoma are global ocular diseases with
high blindness rate. RNA interference (RNAi) is being increasingly used in the treatment of …

Mucoadhesive micro-/nano carriers in ophthalmic drug delivery: an overview

JB Naik, SR Pardeshi, RP Patil, PB Patil, A Mujumdar - BioNanoScience, 2020 - Springer
The eye is a challenging organ for ophthalmic drug delivery due to the barriers associated
with the anterior and posterior segments like nasolacrimal drainage, blinking, induced …

Pharmaceutical implants: Classification, limitations and therapeutic applications

Z Mohtashami, Z Esmaili, MA Vakilinezhad… - Pharmaceutical …, 2020 - Taylor & Francis
Controlled/sustained delivery systems have been developed rapidly which show the ability
to overcome the obstacles of traditional delivery systems. Daily development of biomedical …

Novel Liposome Aggregate Platform (LAP) system for sustained retention of drugs in the posterior ocular segment following intravitreal injection

S Blazaki, K Pachis, M Tzatzarakis, M Tsilimbaris… - International Journal of …, 2020 - Elsevier
Abstract A novel Liposome Aggregate Platform (LAP) system for prolonged retention of
drugs in the posterior eye segment after intravitreal injection (IVT) was developed and …

[HTML][HTML] Tailoring surface properties of liposomes for dexamethasone intraocular administration

MD Al-Amin, F Mastrotto, A Subrizi, M Sen… - Journal of Controlled …, 2023 - Elsevier
Diseases of the posterior eye segment are often characterized by intraocular inflammation,
which causes, in the long term, severe impairment of eye functions and, ultimately, vision …