Sequencing and characterizing short tandem repeats in the human genome

HA Tanudisastro, IW Deveson, H Dashnow… - Nature Reviews …, 2024 - nature.com
Short tandem repeats (STRs) are highly polymorphic sequences throughout the human
genome that are composed of repeated copies of a 1–6-bp motif. Over 1 million variable …

Challenges in analysis and interpretation of microsatellite data for population genetic studies

AI Putman, I Carbone - Ecology and evolution, 2014 - Wiley Online Library
Advancing technologies have facilitated the ever‐widening application of genetic markers
such as microsatellites into new systems and research questions in biology. In light of the …

[HTML][HTML] Mutability of Y-chromosomal microsatellites: rates, characteristics, molecular bases, and forensic implications

KN Ballantyne, M Goedbloed, R Fang, O Schaap… - The American Journal of …, 2010 - cell.com
Nonrecombining Y-chromosomal microsatellites (Y-STRs) are widely used to infer
population histories, discover genealogical relationships, and identify males for criminal …

The landscape of human STR variation

T Willems, M Gymrek, G Highnam, D Mittelman… - Genome …, 2014 - genome.cshlp.org
Short tandem repeats are among the most polymorphic loci in the human genome. These
loci play a role in the etiology of a range of genetic diseases and have been frequently …

lobSTR: a short tandem repeat profiler for personal genomes

M Gymrek, D Golan, S Rosset, Y Erlich - Genome research, 2012 - genome.cshlp.org
Short tandem repeats (STRs) have a wide range of applications, including medical genetics,
forensics, and genetic genealogy. High-throughput sequencing (HTS) has the potential to …

Rise of the machines–recommendations for ecologists when using next generation sequencing for microsatellite development

MG Gardner, AJ Fitch, T Bertozzi… - Molecular Ecology …, 2011 - Wiley Online Library
Next generation sequencing is revolutionizing molecular ecology by simplifying the
development of molecular genetic markers, including microsatellites. Here, we summarize …

Population structure in a comprehensive genomic data set on human microsatellite variation

TJ Pemberton, M DeGiorgio… - G3: Genes, Genomes …, 2013 - academic.oup.com
Over the past two decades, microsatellite genotypes have provided the data for landmark
studies of human population-genetic variation. However, the various microsatellite data sets …

Bringing together linguistic and genetic evidence to test the Bantu expansion

C De Filippo, K Bostoen… - Proceedings of the …, 2012 - royalsocietypublishing.org
The expansion of Bantu languages represents one of the most momentous events in the
history of Africa. While it is well accepted that Bantu languages spread from their homeland …

[HTML][HTML] A reference haplotype panel for genome-wide imputation of short tandem repeats

S Saini, I Mitra, N Mousavi, SF Fotsing… - Nature …, 2018 - nature.com
Short tandem repeats (STRs) are involved in dozens of Mendelian disorders and have been
implicated in complex traits. However, genotyping arrays used in genome-wide association …

A genomic portrait of human microsatellite variation

BA Payseur, P Jing, RJ Haasl - Molecular biology and evolution, 2011 - academic.oup.com
Rapid advances in DNA sequencing and genotyping technologies are beginning to reveal
the scope and pattern of human genomic variation. Although single nucleotide …