Until 2010, colorectal serrated lesions were generally considered as harmless lesions and
reported as hyperplastic polyps (HPs) by pathologists and gastroenterologists. However …

Colorectal cancers (CRCs) arise from precursor polyps whose cellular origins, molecular
heterogeneity, and immunogenic potential may reveal diagnostic and therapeutic insights …

Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …

Importance Noninvasive tests for colorectal cancer screening must include sensitive
detection of colorectal cancer and precancerous lesions. These tests must be validated for …

Background Patients with serrated polyps are at increased risk for post-colonoscopy
colorectal cancer (PCCRC); however, evidence for a dedicated serrated polyp detection rate …

Background/Aim: The utility of mismatch repair (MMR) immunohistochemistry (IHC) and
microsatellite instability (MSI) testing in uterine mesonephric-like adenocarcinoma (MLA) …

BACKGROUND Hyperplastic polyps are considered non-neoplastic, whereas sessile
serrated lesions (SSLs) are precursors of cancer via the ''serrated neoplastic pathway''. The …

Abstract Caudal-type homeobox 2 (CDX2), special AT-rich sequence-binding protein 2
(SATB2), and keratin 20 (KRT20) are frequently used as intestinal epithelium-specific …

Colorectal carcinoma (CRC) is one of the most common type of cancers and a leading
cause of cancer-related deaths worldwide and in the United States. CRC is a …

Neurotrophic tropomyosin receptor kinase (NTRK) gene fusions are emerging tissue‐
agnostic drug targets in malignancies including colorectal carcinomas (CRCs), but their …