[HTML][HTML] The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis

Z Hodzic, AM Bolock, M Good - Frontiers in pediatrics, 2017 - frontiersin.org
Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal disease of
prematurity. Although the precise cause is not well understood, the main risk factors thought …

Gut dysbiosis with bacilli dominance and accumulation of fermentation products precedes late-onset sepsis in preterm infants

S Graspeuntner, S Waschina, S Künzel… - Clinical Infectious …, 2019 - academic.oup.com
Background Gut dysbiosis has been suggested as a major risk factor for the development of
late-onset sepsis (LOS), a main cause of mortality and morbidity in preterm infants. We …

[HTML][HTML] Necrotizing enterocolitis, gut microbiota, and brain development: role of the brain-gut axis

HJ Niemarkt, TG De Meij, C van Ganzewinkel… - Neonatology, 2019 - karger.com
Necrotizing enterocolitis (NEC) is a relatively common disease in very-low-birth-weight
infants and is associated with high mortality and morbidity. In survivors, neurodevelopmental …

[HTML][HTML] Social and psychological adversity are associated with distinct mother and infant gut microbiome variations

BB Warner, BA Rosa, IM Ndao, PI Tarr, JP Miller… - Nature …, 2023 - nature.com
Health disparities are driven by underlying social disadvantage and psychosocial stressors.
However, how social disadvantage and psychosocial stressors lead to adverse health …

Probiotics and the prevention of necrotizing enterocolitis

MA Underwood - Journal of pediatric surgery, 2019 - Elsevier
Background Immaturity of the host immune system and alterations in the intestinal
microbiome appear to be key factors in the pathogenesis of necrotizing enterocolitis (NEC) …

[HTML][HTML] Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing …

Y He, W Du, S Xiao, B Zeng, X She, D Liu, H Du… - Journal of Translational …, 2021 - Springer
Background Necrotizing enterocolitis (NEC) remains a life-threatening disease in neonates.
Numerous studies have shown a correlation between the intestinal microbiota and NEC, but …

[HTML][HTML] Interpretable prediction of necrotizing enterocolitis from machine learning analysis of premature infant stool microbiota

YC Lin, A Salleb-Aouissi, TA Hooven - BMC bioinformatics, 2022 - Springer
Background Necrotizing enterocolitis (NEC) is a common, potentially catastrophic intestinal
disease among very low birthweight premature infants. Affecting up to 15% of neonates born …

Necrotizing enterocolitis and the microbiome: current status and future directions

R Thänert, EC Keen, G Dantas… - The Journal of …, 2021 - academic.oup.com
Decades of research have failed to define the pathophysiology of necrotizing enterocolitis
(NEC), a devastating pediatric gastrointestinal disorder of preterm infants. However …

[HTML][HTML] Evaluation of 16S rRNA primer sets for characterisation of microbiota in paediatric patients with autism spectrum disorder

L Palkova, A Tomova, G Repiska, K Babinska… - Scientific reports, 2021 - nature.com
Abstract intestinal microbiota is becoming a significant marker that reflects differences
between health and disease status also in terms of gut-brain axis communication. Studies …

[HTML][HTML] The metabolome and the gut microbiota for the prediction of necrotizing enterocolitis and spontaneous intestinal perforation: a systematic review

L Moschino, G Verlato, M Duci, ME Cavicchiolo… - Nutrients, 2022 - mdpi.com
Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal emergency in
preterm neonates. Research on early predictive biomarkers is fundamental. This is a …