Stem cell therapy for preventing neonatal diseases in the 21st century: current understanding and challenges

CR Nitkin, J Rajasingh, C Pisano, GE Besner… - Pediatric …, 2020 - nature.com
Diseases of the preterm newborn such as bronchopulmonary dysplasia, necrotizing
enterocolitis, cerebral palsy, and hypoxic-ischemic encephalopathy continue to be major …

Effect of fecal microbiota transplantation route of administration on gut colonization and host response in preterm pigs

A Brunse, L Martin, TS Rasmussen… - The ISME …, 2019 - academic.oup.com
This study examined gut colonization patterns and host responses to fecal microbiota
transplantation (FMT) by different administration routes after preterm birth. In two separate …

Exploring the role of gut bacteria in health and disease in preterm neonates

JKF Lee, LT Hern Tan, A Ramadas… - International journal of …, 2020 - mdpi.com
The mortality rate of very preterm infants with birth weight< 1500 g is as high as 15%. The
survivors till discharge have a high incidence of significant morbidity, which includes …

Early-life lung and gut microbiota development and respiratory syncytial virus infection

K Yagi, N Asai, GB Huffnagle, NW Lukacs… - Frontiers in …, 2022 - frontiersin.org
Several environmental factors can influence the development and establishment of the early-
life microbiota. For example, exposure to different environmental factors from birth to …

Advances in paediatric gastroenterology

PKH Tam, PHY Chung, SD St Peter, CP Gayer… - The Lancet, 2017 - thelancet.com
Recent developments in paediatric gastrointestinal surgery have focused on minimally
invasive surgery, the accumulation of high-quality clinical evidence, and scientific research …

The intestinal microbiome in infectious diseases: the clinical relevance of a rapidly emerging field

VC Harris, BW Haak… - Open forum …, 2017 - academic.oup.com
The field of infectious disease is undergoing a paradigm shift as the intestinal microbiome is
becoming understood. The aim of this review is to inform infectious disease physicians of the …

[HTML][HTML] Necrotizing enterocolitis in premature infants—A defect in the brakes? Evidence from clinical and animal studies

V Sampath, M Martinez, M Caplan, MA Underwood… - Mucosal …, 2023 - Elsevier
A key aspect of postnatal intestinal adaptation is the establishment of symbiotic relationships
with co-evolved gut microbiota. Necrotizing enterocolitis (NEC) is the most severe disease …

Progress of analytical tools and techniques for human gut microbiome research

EJ Song, ES Lee, YD Nam - Journal of Microbiology, 2018 - Springer
Massive DNA sequencing studies have expanded our insights and understanding of the
ecological and functional characteristics of the gut microbiome. Advanced sequencing …

The significance of the enteric microbiome on the development of childhood disease: a review of prebiotic and probiotic therapies in disorders of childhood

J Slattery, DF MacFabe… - Clinical Medicine Insights …, 2016 - journals.sagepub.com
Recent studies have highlighted the fact that the enteric microbiome, the trillions of microbes
that inhabit the human digestive tract, has a significant effect on health and disease …

Dichotomous development of the gut microbiome in preterm infants

TTB Ho, MW Groer, B Kane, AL Yee, BA Torres… - Microbiome, 2018 - Springer
Background Preterm infants are at risk of developing intestinal dysbiosis with an increased
proportion of Gammaproteobacteria. In this study, we sought the clinical determinants of the …