Anticancer potential of the plant‐derived Saponin Gracillin: a comprehensive review of mechanistic approaches

MS Bhuia, R Chowdhury, FA Sonia… - Chemistry & …, 2023 - Wiley Online Library
With the increasing prevalence of cancer and the toxic side effects of synthetic drugs, natural
products are being developed as promising therapeutic approaches. Gracillin is a naturally …

The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities

MAR Mia, D Dey, MR Sakib, MY Biswas… - Phytotherapy …, 2023 - Wiley Online Library
Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

[HTML][HTML] Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain

O Rabie, HAS El-Nashar, MY George… - Biomedicine & …, 2023 - Elsevier
Cyclophosphamide (CPA) is a chemotherapeutic drug used for various types of cancers.
However, patients receiving CPA for long periods suffer cognitive impairment associated …

Chemical composition, seasonal variation and antiaging activities of essential oil from Callistemon subulatus leaves growing in Egypt

O Rabie, HAS El-Nashar, TA Majrashi… - Journal of enzyme …, 2023 - Taylor & Francis
Callistemon is an aromatic genus of flowering plants belonging to family Myrtaceae. The
essential oils of C. subulatus leaves were collected in four seasons and analyzed using …

Comparative metabolic study of the chloroform fraction of three Cystoseira species based on UPLC/ESI/MS analysis and biological activities

SH Aly, AM Elissawy, MA El Hassab… - Journal of Enzyme …, 2024 - Taylor & Francis
This study aims to investigate the phytoconstituents of the chloroform fraction of three
Cystoseira spp. namely C. myrica, C. trinodis, and C. tamariscifolia using UPLC/ESI/MS …

HPLC-ESI/MS-MS characterization of compounds in Dolomiaea costus extract and evaluation of cytotoxic and antiviral properties: molecular mechanisms underlying …

HAS El-Nashar, OA Eldahshan, NFA Fattah… - … Medicine and Therapies, 2023 - Springer
Abstract Background Dolomiaea costus (syn: Saussurea costus; Family Asteraceae)
occupies an important place in the traditional Chinese medicinal plants and is prescribed for …

[HTML][HTML] Phytochemical profiling and mechanistic evaluation of black garlic extract on multiple sclerosis rat model

YA Elkhawas, M Seleem, MI Shabayek… - Journal of Functional …, 2023 - Elsevier
Black garlic aqueous-ethanol extract (BGE) was evaluated for its antioxidant and anti-
inflammatory effects in multiple sclerosis induced-rat model. It was also analyzed using high …

Genus Pimenta: An Updated Comprehensive Review on Botany, Distribution, Ethnopharmacology, Phytochemistry and Biological Approaches

HAS El‐Nashar, AAM Ali, YH Salem - Chemistry & Biodiversity, 2023 - Wiley Online Library
Pimenta is a genus of flowering plants belonging to family Myrtaceae, native to the West
Indies, Mexico, and South America. Numerous traditional uses were reported as anti …

Efficacy of Rotundic acid and its derivatives as promising natural anticancer triterpenoids: A literature‐based study

MS Bhuia, R Chowdhury, FA Sonia… - Chemistry & …, 2024 - Wiley Online Library
Rotundic acid (RA) is a naturally occurring pentacyclic triterpene with a multitude of
pharmacological activities. The primary emphasis of this study is on summarizing the …

HPLC-ESI/MS-MS metabolic profiling of white pitaya fruit and cytotoxic potential against cervical cancer: Comparative studies, synergistic effects, and molecular …

HAS El-Nashar, MA Al-Azzawi, HH Al-Kazzaz… - … of Pharmaceutical and …, 2024 - Elsevier
Natural approach became a high demand for the prevention and treatment of such diseases
for their proven safety and efficacy. This study is aimed to perform comparative …