Mechanisms linking inflammation to insulin resistance

L Chen, R Chen, H Wang… - International journal of …, 2015 - Wiley Online Library
Obesity is now widespread around the world. Obesity‐associated chronic low‐grade
inflammation is responsible for the decrease of insulin sensitivity, which makes obesity a …

Epigenetic programming and fetal metabolic programming

Z Zhu, F Cao, X Li - Frontiers in endocrinology, 2019 - frontiersin.org
Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

Effects of maternal obesity and gestational diabetes mellitus on the placenta: current knowledge and targets for therapeutic interventions

S Bedell, J Hutson, B de Vrijer… - Current vascular …, 2021 - ingentaconnect.com
Obesity and gestational diabetes mellitus (GDM) are becoming more common among
pregnant women worldwide and are individually associated with a number of placenta …

Air pollution and the fetal origin of disease: a systematic review of the molecular signatures of air pollution exposure in human placenta

LJ Luyten, ND Saenen, BG Janssen, K Vrijens… - Environmental …, 2018 - Elsevier
Background Fetal development is a crucial window of susceptibility in which exposure-
related alterations can be induced on the molecular level, leading to potential changes in …

Leptin in pregnancy and development: a contributor to adulthood disease?

JF Briffa, AJ McAinch, T Romano… - American Journal …, 2015 - journals.physiology.org
Emerging research has highlighted the importance of leptin in fetal growth and development
independent of its essential role in the maintenance of hunger and satiety through the …

Altered maternal and placental lipid metabolism and fetal fat development in obesity: Current knowledge and advances in non-invasive assessment

F Delhaes, SA Giza, T Koreman, G Eastabrook… - Placenta, 2018 - Elsevier
Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated
with pregnancy complications such as preeclampsia and gestational diabetes, and offspring …

Developmental programming by maternal obesity in 2015: Outcomes, mechanisms, and potential interventions

NC Penfold, SE Ozanne - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “SBN 2014”. Obesity in women of child-bearing age is a
growing problem in developed and developing countries. Evidence from human studies …

Bisphenol A: Targeting metabolic tissues

N Chevalier, P Fénichel - Reviews in Endocrine and Metabolic Disorders, 2015 - Springer
The prevalence of obesity, metabolic syndrome and type 2 diabetes has dramatically
increased worldwide over the last few decades. Although genetic predisposition and lifestyle …

A birth cohort study to investigate the association between prenatal phthalate and bisphenol A exposures and fetal markers of metabolic dysfunction

J Ashley-Martin, L Dodds, TE Arbuckle, AS Ettinger… - Environmental …, 2014 - Springer
Background Obesity and type-2 diabetes are on the rise and in utero exposure to
environmental contaminants is a suspected contributing factor. Our objective was to …

Maternal obesity and inflammatory mediators: A controversial association

KPT Pendeloski, E Ono, MR Torloni… - American Journal of …, 2017 - Wiley Online Library
The link between maternal obesity and inflammatory mediators is still unclear. Our aim was
to summarize the main findings of recently published studies on this topic. We performed a …