Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …

Simple Summary Anaplastic thyroid carcinoma (ATC) has a dismal prognostic.
Chemotherapy and radiotherapy are the mainstem options for patients with ATC. In selected …

Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Since the guidelines for the management of ATC by the American Thyroid …

Background: Anaplastic thyroid carcinoma (ATC) and metastatic poorly differentiated thyroid
carcinomas (PDTCs) are rare aggressive malignancies with poor overall survival (OS) …

The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated
thyroid cancer (DTC); however, the complex intratumor transformation process is poorly …

Tumours can arise from thyroid follicular cells if they acquire driver mutations that
constitutively activate the MAPK signalling pathway. In addition, a limited set of additional …

Anaplastic thyroid cancer (ATC) is one of the most lethal of all cancers. It is more common in
women and occurs primarily in older patients. ATC has a median overall survival of 3–5 …

Abstract Purpose of Review Anaplastic thyroid carcinoma is a type of thyroid carcinoma with
the most aggressive biological behaviour amongst thyroid cancer. Here, we review the …

Differentiated thyroid cancers (DTCs) are primarily initiated by mutations that activate the
MAPK signaling cascade, typically at BRAF or RAS oncoproteins. DTCs can evolve to more …

Anaplastic thyroid cancer (ATC) is an extremely aggressive but rare form of thyroid
malignancy, making up only 1% to 2% of all thyroid cancers. 1 Although the incidence of …