Organizing multi-enzyme systems into programmable materials for biocatalysis

MJ Seo, C Schmidt-Dannert - Catalysts, 2021 - mdpi.com
Significant advances in enzyme discovery, protein and reaction engineering have
transformed biocatalysis into a viable technology for the industrial scale manufacturing of …

Kaleidoscope megamolecules synthesis and application using self-assembly technology

S Zhou, Y Wei - Biotechnology Advances, 2023 - Elsevier
The megamolecules with high ordered structures play an important role in chemical biology
and biomedical engineering. Self-assembly, a long-discovered but very appealing …

De novo designed peptide and protein hairpins self‐assemble into sheets and nanoparticles

JM Galloway, HEV Bray, DK Shoemark, LR Hodgson… - Small, 2021 - Wiley Online Library
The design and assembly of peptide‐based materials has advanced considerably, leading
to a variety of fibrous, sheet, and nanoparticle structures. A remaining challenge is to …

Crystalline state determines the potency of galectin-10 protein assembly to induce inflammation

Y Zhao, S Mo, L Yu, X Li, Y Hao, W Zhang, Q Zhang… - Nano Letters, 2022 - ACS Publications
Protein crystallization is a prevalent phenomenon existing in the formation of intricate protein-
assembled structures in living cells. Whether the crystallization of a protein would exert a …

1D alignment of proteins and other nanoparticles by using reversible covalent bonds on cyclic peptide nanotubes

JM Priegue, I Louzao, I Gallego… - Organic Chemistry …, 2022 - pubs.rsc.org
Self-assembling cyclic peptide nanotubes are supramolecular structures whose diameter
and external surface properties are precisely controlled. In this communication we describe …

[HTML][HTML] Biomedical applications of supramolecular materials in the controllable delivery of steroids

Y Hao, F Zhang, S Mo, J Zhao, X Wang… - Frontiers in Molecular …, 2021 - frontiersin.org
Glucocorticoids are a class of steroid hormones secreted from the adrenal glands. The
strong anti-inflammatory effects make it be one of the most popular and versatile drugs …

β-Sheet Assembly Translates Conservative Single-Site Mutation into a Perturbation in Macroscopic Structure

W Zhang, M Liu, Y Wang, X Wang, R Wang, S Li… - Nano Letters, 2023 - ACS Publications
Transferring structural information from amino acid sequence to macroscale assembly is a
challenging approach for designing protein quaternary structure. However, the pathway by …

Flexible assembly of engineered Tetrahymena ribozymes forming polygonal RNA nanostructures with catalytic ability

Y Mori, H Oi, Y Suzuki, K Hidaka, H Sugiyama… - …, 2021 - Wiley Online Library
Ribozymes with modular architecture constitute an attractive class of structural platforms for
design and construction of nucleic acid nanostructures with biological functions. Through …

Biomimetic construction of artificial selenoenzymes

H Zhao, C Xu, T Wang, J Liu - Biomimetics, 2023 - mdpi.com
Selenium exists in the form of selenocysteines in selenoproteins and plays a pivotal role in
the catalytic process of the antioxidative enzymes. In order to study the structural and …

[HTML][HTML] Conservation and identity selection of cationic residues flanking the hydrophobic regions in intermediate filament superfamily

W Zhang, M Liu, RL Dupont, K Huang, L Yu… - Frontiers in …, 2021 - frontiersin.org
The interplay between the hydrophobic interactions generated by the nonpolar region and
the proximal functional groups within nanometers of the nonpolar region offers a promising …