Lung cancer is a major global health problem, as it is the leading cause of cancer-related
deaths worldwide. Major advances in the identification of key mutational alterations have led …

Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …

Obesity is a global issue, and it leads to various health comorbidities like cardiovascular
disease, diabetes type II and certain cancers. The relationship between obesity and cancer …

68 Ga-fibroblast activation protein inhibitors (FAPIs) 2, 4, and 46 have already been
proposed as promising PET tracers. However, the short half-life of 68 Ga (68 min) creates …

Lung cancer is the leading cause of cancer-related mortality worldwide. Although the
PI3K/Akt/mTOR signaling pathway has recently been considered as one of the most altered …

Lung cancer is the most common cause of cancer deaths worldwide. The two broad
histological subtypes of lung cancer are small-cell lung cancer (SCLC), which is the cause of …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in the
world. Immunological analysis of the tumor microenvironment (immunoscore) shows great …

A malignant tumor is not merely an accumulation of neoplastic cells, but constitutes a
microenvironment containing endothelial cells, fibroblasts, structural components, and …

Background Erlotinib has been shown to improve progression-free survival compared with
chemotherapy when given as first-line treatment for Asian patients with non-small-cell lung …

Ubiquitin-specific protease 14 (USP14), a deubiquitinating enzyme (DUB), is associated
with proteasomes and exerts a dual function in regulating protein degradation. USP14 …