Restorative effect of fucoxanthin in an ovalbumin-induced allergic rhinitis animal model through NF-κB p65 and STAT3 signaling

S Li, Y Zhang, VP Veeraraghavan… - Journal of …, 2019 - dl.begellhouse.com
Allergic rhinitis is a sensitivity to allergens that causes swelling or puffiness of the nasal
airways. The occurrence of allergic rhinitis is mounting worldwide. We examined whether …

Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice

XY Bai, P Liu, YW Chai, Y Wang, SH Ren, YY Li… - European journal of …, 2020 - Elsevier
Steroidal agent is a standard clinical treatment of atopic dermatitis; however, have serious
side effects. Artesunate is reported to exhibit anti-inflammatory properties although its effect …

[HTML][HTML] Promising strategies employing nucleic acids as antimicrobial drugs

L Moreira, NM Guimarães, RS Santos… - … Therapy-Nucleic Acids, 2024 - cell.com
Antimicrobial resistance (AMR) is a growing concern because it causes microorganisms to
develop resistance to drugs commonly used to treat infections. This results in increased …

[HTML][HTML] Counteracting health risks by Modulating Homeostatic Signaling

JJ Tian, M Levy, X Zhang, R Sinnott… - Pharmacological research, 2022 - Elsevier
Homeostasis was initially conceptualized by Bernard and Cannon around a century ago as
a steady state of physiological parameters that vary within a certain range, such as blood …

MiR-146a mimic attenuates murine allergic rhinitis by downregulating TLR4/TRAF6/NF-κB pathway

J Wang, Z Cui, L Liu, S Zhang, Y Zhang, Y Zhang… - …, 2019 - Future Medicine
Aim: This study aims to investigate whether microRNA (miR)-146a exerts therapeutic
potential to allergic rhinitis (AR). Methods: Female BALB/c mice were randomly divided into …

Diesel exhaust particles increase nasal symptoms and IL-17A in house dust mite-induced allergic mice

HJ Jung, YK Ko, WS Shim, HJ Kim, DY Kim… - Scientific Reports, 2021 - nature.com
Diesel exhaust particles (DEPs), traffic-related air pollutants, are considered environmental
factors adversely affecting allergic diseases. However, the immunological basis for the …

[HTML][HTML] Long noncoding RNA Linc00632 inhibits interleukin-13-induced inflammatory cytokine and mucus production in nasal epithelial cells

L Yue, X Yin, F Hao, J Dong, X Ren, O Xu… - Journal of innate …, 2020 - karger.com
Allergic rhinitis (AR) is an allergic disease characterized as (immunoglobulin E)-mediated
type I hypersensitivity disorder. The interleukin-13 (IL-13) signaling pathway has been …

Stem cells from human exfoliated deciduous teeth correct the immune imbalance of allergic rhinitis via Treg cells in vivo and in vitro

YY Dai, SY Ni, K Ma, YS Ma, ZS Wang… - Stem Cell Research & …, 2019 - Springer
Background Several studies have demonstrated that mesenchymal stem cells can
ameliorate the inflammation of allergic rhinitis (AR) and correct the Th1/Th2 immune …

Avenanthramide C from germinated oats exhibits anti-allergic inflammatory effects in mast cells

H Dhakal, EJ Yang, S Lee, MJ Kim, MC Baek, B Lee… - Scientific Reports, 2019 - nature.com
Mast cells play a crucial role in allergic diseases via the release of inflammatory mediators,
particularly histamine and pro-inflammatory cytokines. Avenanthramide (Avn) C, a …

Apigenin attenuates allergic responses of ovalbumin-induced allergic rhinitis through modulation of Th1/Th2 responses in experimental mice

F Chen, D He, B Yan - Dose-Response, 2020 - journals.sagepub.com
Background: Allergic rhinitis (AR) is an immunoglobulin E (IgE)-mediated immune-
inflammatory response mainly affecting nasal mucosa. Apigenin, a flavonoid, has been …