Cell excitability and its modulation by hormones and neurotransmitters involve the concerted
action of a large repertoire of membrane proteins, especially ion channels. Unique …

Decades of research have investigated the mechanisms that lead to the origin of cancer,
striving to identify tumor-initiating cells. These cells, also known as cancer stem cells, are …

Normal high-density lipoprotein (nHDL) can induce angiogenesis in healthy individuals.
However, HDL from patients with coronary artery disease undergoes various modifications …

Objective Emerging evidence suggests that brain angiotensin-(1–7)(Ang-(1–7)) deficiency
contributes to the pathogenesis of Alzheimer's disease (AD). Meanwhile, our previous …

In healthy vessels, endothelial cells maintain a stable, differentiated, and growth-arrested
phenotype for years. Upon injury, a rapid phenotypic switch facilitates proliferation to restore …

Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the
expression of target genes, impact on the cellular phenotype and cardiovascular disease …

Long non-coding RNAs (lncRNAs) impact cell function via numerous mechanisms. In the
nucleus, interactions between lncRNAs and DNA and the consequent formation of non …

LncRNAs are involved in many physiological and pathological processes, including
chromatin remodeling, transcription, posttranscriptional gene expression, mRNA stability …

The Hippo signaling pathway was found coordinately modulates cell regeneration and
organ size. Its dysregulation contributes to uncontrolled cell proliferation and malignant …

Cytogenetics and genomics have completely transformed our understanding of evolutionary
genome change since the early 1950s. The point of this paper is to outline some of the …