Mitochondrial quality control in cerebral ischemia–reperfusion injury
M Wu, X Gu, Z Ma - Molecular Neurobiology, 2021 - Springer
Ischemic stroke is one of the leading causes of death and also a major cause of adult
disability worldwide. Revascularization via reperfusion therapy is currently a standard …
disability worldwide. Revascularization via reperfusion therapy is currently a standard …
Mitochondrial effects of common cardiovascular medications: the good, the bad and the mixed
AM Bețiu, L Noveanu, IM Hâncu, A Lascu… - International Journal of …, 2022 - mdpi.com
Mitochondria are central organelles in the homeostasis of the cardiovascular system via the
integration of several physiological processes, such as ATP generation via oxidative …
integration of several physiological processes, such as ATP generation via oxidative …
Irisin Rescues Blood‐Brain Barrier Permeability following Traumatic Brain Injury and Contributes to the Neuroprotection of Exercise in Traumatic Brain Injury
P Guo, Z Jin, J Wang, A Sang… - Oxidative medicine and …, 2021 - Wiley Online Library
Traumatic brain injury (TBI) has a high incidence, mortality, and morbidity all over the world.
One important reason for its poor clinical prognosis is brain edema caused by blood‐brain …
One important reason for its poor clinical prognosis is brain edema caused by blood‐brain …
[HTML][HTML] Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt …
L Liu, Q Cao, W Gao, B Li, Z Xia, B Zhao - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Diabetic patients are more vulnerable to cerebral ischemia-reperfusion (CIR) injury and
have a worse prognosis and higher mortality after ischemic stroke than non-diabetic …
have a worse prognosis and higher mortality after ischemic stroke than non-diabetic …
Verapamil alleviates myocardial ischemia/reperfusion injury by attenuating oxidative stress via activation of SIRT1
M Bao, W Huang, Y Zhao, X Fang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Myocardial ischemia/reperfusion (I/R) injury is a potential complication of ischemic heart
disease after recanalization. One of the primary reasons for I/R injury is the excessive …
disease after recanalization. One of the primary reasons for I/R injury is the excessive …
Combination of puerarin and tanshinone IIA alleviates ischaemic stroke injury in rats via activating the Nrf2/ARE signalling pathway
Q Miao, R Wang, X Sun, S Du, L Liu - Pharmaceutical Biology, 2022 - Taylor & Francis
Abstract Context Puerarin (Pue) and tanshinone IIA (Tan IIA) are often used in combination
in the treatment of cerebrovascular diseases. Objective To investigate the neuroprotective …
in the treatment of cerebrovascular diseases. Objective To investigate the neuroprotective …
Verapamil inhibits TXNIP-NLRP3 inflammasome activation and preserves functional recovery after intracerebral hemorrhage in mice
Intracerebral hemorrhage (ICH) is the second most common type of stroke with no
satisfactory treatment. Recent studies from our group and others indicated a potential …
satisfactory treatment. Recent studies from our group and others indicated a potential …
Enhanced neuroprotective effect of verapamil-loaded hyaluronic acid modified carbon quantum dots in an in-vitro model of amyloid-induced Alzheimer's disease
EM Mosalam, HM Abdel-Bar, AI Elberri… - International Journal of …, 2024 - Elsevier
This study aims to investigate the molecular mechanisms and the neuroprotective effect of
hyaluronic acid modified verapamil-loaded carbon quantum dots (VRH-loaded HA-CQDs) …
hyaluronic acid modified verapamil-loaded carbon quantum dots (VRH-loaded HA-CQDs) …
Relevance of mitochondrial oxidative stress to arrhythmias: innovative concepts to target treatments
C Liu, N Ma, Z Guo, Y Zhang, J Zhang, F Yang… - Pharmacological …, 2022 - Elsevier
Cardiac arrhythmia occurs frequently worldwide, and in severe cases can be fatal.
Mitochondria are the power plants of cardiomyocytes. In recent studies, mitochondria under …
Mitochondria are the power plants of cardiomyocytes. In recent studies, mitochondria under …
Preliminary evaluation of the antiglycoxidant activity of verapamil using various in vitro and in silico biochemical/biophysical methods
M Nesterowicz, KK Lauko, K Dańkowska… - Frontiers in …, 2023 - frontiersin.org
Introduction: Glycoxidative stress is essential for linking glucose disturbances and
cardiovascular diseases. Unfortunately, contemporary antidiabetic drugs do not have an …
cardiovascular diseases. Unfortunately, contemporary antidiabetic drugs do not have an …