Although deficiencies in polyphenol intake do not result in specific deficiency diseases,
adequate intake of polyphenols could confer health benefits, especially with regard to …

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Resveratrol is a nutraceutical with several therapeutic effects. It has been shown to mimic
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …

Liver fibrosis is a reversible wound-healing process aimed at maintaining organ integrity,
and presents as the critical pre-stage of liver cirrhosis, which will eventually progress to …

Resveratrol is a polyphenol which has been shown to have beneficial effects on metabolic
syndrome-related alterations in experimental animals, including glucose and lipid …

Gut microbiota plays a role in the pathophysiology of metabolic diseases, which include
nonalcoholic fatty liver diseases, through the gut–liver axis. To date, clinical guidelines …

ATP citrate lyase (ACLY) is an important enzyme linking carbohydrate to lipid metabolism by
generating acetyl-CoA from citrate for fatty acid and cholesterol biosynthesis. Mendelian …

The human diet and dietary patterns are closely linked to the health status. High-calorie
Western-style diets have increasingly come under scrutiny as their caloric load and …

Polyphenols (PLPs), phytochemicals found in a wide range of plant-based foods, have
gained extensive attention in view of their antioxidant, anti-inflammatory, immunomodulatory …

Resveratrol is a natural polyphenol that has been reported to reduce the risk of obesity and
nonalcoholic fatty liver disease (NAFLD). Recent evidence has demonstrated that the gut …