Application of mesoporous silica nanoparticles in cancer therapy and delivery of repurposed anthelmintics for cancer therapy

M Koohi Moftakhari Esfahani, SE Alavi, PJ Cabot… - Pharmaceutics, 2022 - mdpi.com
This review focuses on the biomedical application of mesoporous silica nanoparticles
(MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and …

Mesoporous silica nanoparticles: Synthesis methods and their therapeutic use-recent advances

M Ghaferi, M Koohi Moftakhari Esfahani… - Journal of Drug …, 2021 - Taylor & Francis
Mesoporous silica nanoparticles (MSNPs) are a particular example of innovative
nanomaterials for the development of drug delivery systems. MSNPs have recently received …

SiRNA conjugated nanoparticles—a next generation strategy to treat lung cancer

R Itani, A Al Faraj - International journal of molecular sciences, 2019 - mdpi.com
Despite major progress in both therapeutic and diagnostic techniques, lung cancer is still
considered the leading cause of cancer mortality in the world due to the ineffectiveness of …

Nanomedicine for glioblastoma: Progress and future prospects

I Khan, MH Baig, S Mahfooz, MA Imran, MI Khan… - Seminars in Cancer …, 2022 - Elsevier
Glioblastoma is the most aggressive form of brain tumor, accounting for the highest mortality
and morbidity rates. Current treatment for patients with glioblastoma includes maximal safe …

Preparation, characterization, and evaluation of cisplatin-loaded polybutylcyanoacrylate nanoparticles with improved in vitro and in vivo anticancer activities

M Ghaferi, S Amari, B Vivek Mohrir, A Raza… - Pharmaceuticals, 2020 - mdpi.com
This study aimed to evaluate the therapeutic efficacy of the cisplatin encapsulated into
polybutylcyanoacrylate (PBCA) nanoparticles for the treatment of kidney cancer. The …

In vivo glioblastoma therapy using targeted liposomal cisplatin

MS Ashrafzadeh, A Akbarzadeh… - International journal …, 2020 - Taylor & Francis
Background: Drug delivery systems have demonstrated promising results to cross blood–
brain barrier (BBB) and deliver the loaded therapeutics to the brain tumor. This study aims to …

Camel milk as an alternative treatment regimen for diabetes therapy

H Hussain, FH Wattoo, MHS Wattoo… - Food science & …, 2021 - Wiley Online Library
Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its
unique composition helps to regulate the blood glucose level. The current study is aimed to …

Hypoxia‐Responsive Nanoscale Coordination Polymer Enhances the Crosstalk Between Ferroptosis and Immunotherapy

C Cai, J Zhu, X Huang, C Xu, Z Wang… - Advanced Functional …, 2023 - Wiley Online Library
The immunosuppressive tumor microenvironment (TME) severely limits the clinical
applications of cancer immunotherapy. Herein, a hypoxia‐responsive delivery system is …

Enhanced efficacy of PEGylated liposomal cisplatin: In vitro and in vivo evaluation

M Ghaferi, MJ Asadollahzadeh, A Akbarzadeh… - International journal of …, 2020 - mdpi.com
This study aims to evaluate the potency of cisplatin (Cispt)-loaded liposome (LCispt) and
PEGylated liposome (PLCispt) as therapeutic nanoformulations in the treatment of bladder …

PEGylated Mesoporous Silica Nanoparticles (MCM-41): A promising carrier for the targeted delivery of fenbendazole into prostrate cancer cells

MKM Esfahani, SE Alavi, PJ Cabot, N Islam, EL Izake - Pharmaceutics, 2021 - mdpi.com
Low water solubility and thus low bioavailability limit the clinical application of fenbendazole
(FBZ) as a potential anticancer drug. Solubilizing agents, such as Mobil Composition of …