GLP-1 peptide analogs for targeting pancreatic beta cells
SE Alavi, HE Shahmabadi - Drug Discovery Today, 2021 - Elsevier
Loss or dysfunction of the pancreatic beta cells or insulin receptors leads to diabetes
mellitus (DM). This usually occurs over many years; therefore, the development of methods …
mellitus (DM). This usually occurs over many years; therefore, the development of methods …
Cisplatin uptake and release assessment from hydrogel synthesized in acidic and neutral medium: An experimental and molecular dynamics simulation study
I Salahshoori, Z Ramezani, I Cacciotti… - Journal of Molecular …, 2021 - Elsevier
Targeted drug delivery systems (TDDS) are currently considered to overcome traditional
drug delivery systems' criticisms and weaknesses. Biodegradable hydrogels are widely …
drug delivery systems' criticisms and weaknesses. Biodegradable hydrogels are widely …
Nanomaterials for the diagnosis and treatment of head and neck cancers: A review
Head and neck cancer (HNC) is a category of cancers that typically arise from the nose-,
mouth-, and throat-lining squamous cells. The later stage of HNC diagnosis significantly …
mouth-, and throat-lining squamous cells. The later stage of HNC diagnosis significantly …
Development of thiabendazole-loaded mesoporous silica nanoparticles for cancer therapy
MKM Esfahani, N Islam, PJ Cabot… - … Biomaterials Science & …, 2021 - ACS Publications
Thiabendazole (TBZ) is an anthelmintic drug currently studied for anticancer purposes.
However, due to its low solubility, its biomedical application has been limited. Using …
However, due to its low solubility, its biomedical application has been limited. Using …
Optimized methods for the production and bioconjugation of site-specific, alkyne-modified glucagon-like peptide-1 (GLP-1) analogs to azide-modified delivery …
This study aimed to develop and optimize chemistries to produce alkyne-modified glucagon-
like peptide-1 (7–36)-amide (GLP-1 (7–36)-NH2) libraries, which could be rapidly and …
like peptide-1 (7–36)-amide (GLP-1 (7–36)-NH2) libraries, which could be rapidly and …
Challenges in Optimizing Nanoplatforms Used for Local and Systemic Delivery in the Oral Cavity
In this study, we focused on innovative approaches to improve drug administration in oral
pathology, especially by transmucosal and transdermal pathways. These improvements …
pathology, especially by transmucosal and transdermal pathways. These improvements …
A topical gel nanoformulation of amphotericin B (AmB) for the treatment of cutaneous leishmaniasis (CL)
R Boshrouyeh, S Amari… - Journal of Sol-Gel …, 2023 - Springer
This study aimed to improve the water solubility and cutaneous permeability of Amphotericin
B (AmB) for the topical treatment of Leishmania major-induced cutaneous leishmaniasis …
B (AmB) for the topical treatment of Leishmania major-induced cutaneous leishmaniasis …
The Synergistic Anticancer Effect of Dual Drug‐(Cisplatin/Epigallocatechin Gallate) Loaded Gelatin Nanoparticles for Lung Cancer Treatment
YJ Chen, ZW Wang, TL Lu, CB Gomez… - Journal of …, 2020 - Wiley Online Library
Lung cancer has the highest mortality of any cancer worldwide, and cisplatin is a first‐line
chemotherapeutic agent for lung cancer treatment. Unfortunately, cisplatin resistance is a …
chemotherapeutic agent for lung cancer treatment. Unfortunately, cisplatin resistance is a …
[HTML][HTML] Enhancing the efficacy of albendazole for liver cancer treatment using mesoporous silica nanoparticles: An in vitro study
M Ghaferi, W Zahra, A Akbarzadeh, HE Shahmabadi… - Excli Journal, 2022 - ncbi.nlm.nih.gov
The present study aimed to synthesize albendazole (ABZ)-loaded Mobil Composition of
Matter No. 41 (MCM-41 NPs) to increase the efficacy of the drug against liver cancer. ABZ …
Matter No. 41 (MCM-41 NPs) to increase the efficacy of the drug against liver cancer. ABZ …
Inhibitory effects of brusatol delivered using glycosaminoglycan‑placental chondroitin sulfate A‑modified nanoparticles on the proliferation, migration and invasion of …
X Chen, T Yin, B Zhang, B Sun… - International …, 2020 - spandidos-publications.com
Breakthroughs in cancer management result from the development of drugs that can be
used for early diagnosis and effective treatment. Surgery, chemotherapy, radiotherapy and …
used for early diagnosis and effective treatment. Surgery, chemotherapy, radiotherapy and …