An expanding body of evidence continues to build on the role of platelets as initial actors in
the development of atherosclerotic lesions. Platelets bind to leukocytes and endothelial …

Proteins are essential elements for life. They are building blocks of all organisms and the
operators of cellular functions. Humans produce a repertoire of at least 30,000 different …

Recruitment of human CD34+ progenitor cells toward vascular lesions and differentiation
into vascular cells has been regarded as a critical initial step in atherosclerosis. Previously …

Platelet hyperactivity associated with hyperlipidemia may contribute to development of a
prothrombotic state. We previously showed that oxidized low-density lipoprotein (oxLDL) …

Age-related, diet-related and protein conformational diseases, such as atherosclerosis,
diabetes mellitus, cancer, hypercholesterolemia, cardiovascular and neurodegenerative …

In the last decade, it was recognized that platelets and lipoproteins play a pivotal role in both
early and late atherogenesis. Beside cellular interactions of platelets with other blood cells …

Dyslipidaemia leads to proatherogenic oxidative lipid stress that promotes vascular
inflammation and thrombosis, the pathologies that underpin myocardial infarction, stroke …

Background/Aims: Oxidized low-density lipoprotein (oxLDL) promotes unregulated platelet
activation in patients with dyslipidemic disorders. Although oxLDL stimulates activating …

Objective—The interaction of platelets with low density lipoprotein (LDL) contributes to the
development of cardiovascular disease. Platelets are activated by native LDL (nLDL) …

The physiological effect of Lp (a) on platelet activity is unclear. Previous studies explored the
relationship between Lp (a) and platelet aggregation in patients taking statins and …