Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies

J Morze, C Wittenbecher, L Schwingshackl… - Diabetes …, 2022 - Am Diabetes Assoc
BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …

Metabolite biomarkers of type 2 diabetes mellitus and pre-diabetes: A systematic review and meta-analysis

J Long, Z Yang, L Wang, Y Han, C Peng, C Yan… - BMC endocrine …, 2020 - Springer
Background We aimed to explore metabolite biomarkers that could be used to identify pre-
diabetes and type 2 diabetes mellitus (T2DM) using systematic review and meta-analysis …

Targeted metabolomics analysis of amino acids and acylcarnitines as risk markers for diabetes by LC–MS/MS technique

S Hosseinkhani, B Arjmand, A Dilmaghani-Marand… - Scientific Reports, 2022 - nature.com
Diabetes is a common chronic disease affecting millions of people worldwide. It underlies
various complications and imposes many costs on individuals and society. Discovering early …

Distinctive metabolomics patterns associated with insulin resistance and type 2 diabetes mellitus

X Gu, M Al Dubayee, A Alshahrani… - Frontiers in molecular …, 2020 - frontiersin.org
Obesity is associated with an increased risk of insulin resistance (IR) and type 2 diabetes
mellitus (T2DM) which is a multi-factorial disease associated with a dysregulated …

Plasma amino acids metabolomics' important in glucose management in type 2 diabetes

A Alqudah, M Wedyan, E Qnais, H Jawarneh… - Frontiers in …, 2021 - frontiersin.org
The perturbation in plasma free amino acid metabolome has been observed previously in
diabetes mellitus, and is associated with insulin resistance as well as the onset of …

[HTML][HTML] Abnormal tryptophan catabolism in diabetes mellitus and its complications: opportunities and challenges

J Gao, T Yang, B Song, X Ma, Y Ma, X Lin… - Biomedicine & …, 2023 - Elsevier
In recent years, the incidence rate of diabetes mellitus (DM), including type 1 diabetes
mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM) …

Nutritional metabolites in Brassica rapa subsp. chinensis var. parachinensis (choy sum) at three different growth stages: Microgreen, seedling and adult plant

L Zou, WK Tan, Y Du, HW Lee, X Liang, J Lei… - Food Chemistry, 2021 - Elsevier
Choy sum is a commonly consumed Asian green leafy brassica vegetable. A
comprehensive spectrum of nutritional important metabolites, including amino acids, plant …

Dyslipidemia: a trigger for coronary heart disease in Romanian patients with diabetes

MA Găman, MA Cozma, EC Dobrică, N Bacalbașa… - Metabolites, 2020 - mdpi.com
Previous studies have reported age and gender disparities in the occurrence and
therapeutic approach of dyslipidemia and (or) coronary heart disease (CHD) in patients with …

Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: results from the Nurses' Health Study

C Wittenbecher, M Guasch-Ferre, DE Haslam… - …, 2022 - thelancet.com
Background Metabolomics profiles were consistently associated with type 2 diabetes (T2D)
risk, but evidence on long-term metabolite changes and T2D incidence is lacking. We …

Identification of a circulating amino acid signature in frail older persons with type 2 diabetes mellitus: Results from the metabofrail study

R Calvani, L Rodriguez-Mañas, A Picca, F Marini… - Nutrients, 2020 - mdpi.com
Diabetes and frailty are highly prevalent conditions that impact the health status of older
adults. Perturbations in protein/amino acid metabolism are associated with both functional …