The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
MR Player, PF Torrence - Pharmacology & therapeutics, 1998 - Elsevier
The 2–5A system is an RNA degradation pathway that can be induced by the interferons
(IFNs). Treatment of cells with IFN activates genes encoding several double-stranded RNA …
(IFNs). Treatment of cells with IFN activates genes encoding several double-stranded RNA …
Toward an ideal synthesis of oligonucleotides: Development of a novel phosphoramidite method with high capability
Y Hayakawa - Bulletin of the chemical society of Japan, 2001 - academic.oup.com
Several novel methods for reliably carrying out the oligonucleotide synthesis via the
phosphoramidite strategy have been developed. The first is the method using …
phosphoramidite strategy have been developed. The first is the method using …
Uranyl ion as a highly effective catalyst for internucleotide bond formation.
H Sawai, K Kuroda, T Hojo - Bulletin of the Chemical Society of Japan, 1989 - jlc.jst.go.jp
Uranyl ion catalyzes the polymerization of adenosine-5′-phosphorimidazolide very
efficiently in aqueous solution. Up to 95% of the input adenosine-5′-phosphorimidazolide …
efficiently in aqueous solution. Up to 95% of the input adenosine-5′-phosphorimidazolide …
Stereospecific synthesis of (Rp)-and (Sp)-thymidylyl (3′, 5′) thymidylyl methanephosphonates
ZJ Leśnikowski, PJ Wołkanin, WJ Stec - Tetrahedron letters, 1987 - Elsevier
Abstract (Rp)-and (Sp)-diastereomers of thymidylyl (3′, 5′) thymidylyl
methanephosphonate (3) were prepared in the reaction of (Sp)-or (Rp)-isomers of 5′-O …
methanephosphonate (3) were prepared in the reaction of (Sp)-or (Rp)-isomers of 5′-O …
Studies on stereospecific formation of P-chiral internucleotide linkage: Synthesis of diastereoisomeric 2'-deoxyadenylyl (3', 5') 2'-deoxynyle s-mythilphosphorothioates …
ZJ Leśnikowski, A Sibińska - Tetrahedron, 1986 - Elsevier
Substitution of 4-nitrophenoxy group at phosphorus atom of 5'-O-monomethoxytrityl-2'-
deoxyadenosine 3'-O-¦ O-(4-nitrophenyl)-S-methyl-phosphorothioate¦(4)¦(Sp)-4:(Rp)-4= 90 …
deoxyadenosine 3'-O-¦ O-(4-nitrophenyl)-S-methyl-phosphorothioate¦(4)¦(Sp)-4:(Rp)-4= 90 …
Regiocontrolled General Synthesis of Branch-Type 2′-5′-Linked Oligoadenylates
Y Hayakawa, M Hirose, R Noyori - Nucleosides & Nucleotides, 1989 - Taylor & Francis
Regiocontrolled General Synthesis of Branch-Type 2′-5′-Linked Oligoadenylates Page 1
NUCLEOSIDES & NUCLEOTIDES, 8(5&6), 867-870 (1989) REGIOCONTROLLED …
NUCLEOSIDES & NUCLEOTIDES, 8(5&6), 867-870 (1989) REGIOCONTROLLED …
Chemical Synthesis of Fully and Partially Xyloadenosine-Substituted 2′, 5′-Oligoadenylates Designed as New Potential Antiviral and Antitumor Agents
S Huss, G Gosselin, A Pompon… - Nucleosides & …, 1986 - Taylor & Francis
Abstract Seven 2′, 5′-oligoadenylate analogues containing 9-β-D-xylofuranosyladenine
(xyloaadenosine, XyloA) at the 2′-end or at other positions were synthesized by the …
(xyloaadenosine, XyloA) at the 2′-end or at other positions were synthesized by the …
Spectroscopic and enzymatic characterization of 2′–5′ and 3′–5′ RNA hexamers AACCUU synthesised by phosphotriester approach in solution using 2′-t …
V Gopalakrishnan, KN Ganesh, A Gunjal, SM Likhite - Tetrahedron, 1991 - Elsevier
Comparative 1H, 31P NMR and CD spectroscopic results and enzymatic cleavage of single
stranded RNA hexamers which have identical base sequence (AACCUU) but are …
stranded RNA hexamers which have identical base sequence (AACCUU) but are …
DNA synthesis without base protection
M Sekine - Current Protocols in Nucleic Acid Chemistry, 2004 - Wiley Online Library
DNA synthesis can be achieved by using O‐selective methods for internucleotide bond
formation. This greatly simplifies the synthesis of oligodeoxyribonucleotides by eliminating …
formation. This greatly simplifies the synthesis of oligodeoxyribonucleotides by eliminating …
[PDF][PDF] Bacterial class A acid phosphatases as versatile tools in organic synthesis
T Van Herk - Faculty of Science, Institutional Repository of the …, 2008 - dare.uva.nl
The role of phosphate esters is vitally important for all cell processes.[1-3] They play an
essential part in photosynthesis, carbohydrate and lipid metabolism, the nitrogen cycle …
essential part in photosynthesis, carbohydrate and lipid metabolism, the nitrogen cycle …