Current and novel treatment options for obstructive sleep apnoea

W Randerath, J de Lange, J Hedner… - ERJ open …, 2022 - Eur Respiratory Soc
Obstructive sleep apnoea is a challenging medical problem due to its prevalence, its impact
on quality of life and performance in school and professionally, the implications for risk of …

Comparative efficacy and safety of wakefulness-promoting agents for excessive daytime sleepiness in patients with obstructive sleep apnea: a systematic review and …

T Pitre, J Mah, S Roberts, K Desai, Y Gu… - Annals of Internal …, 2023 - acpjournals.org
Background: Excessive daytime sleepiness (EDS) is common among patients with
obstructive sleep apnea (OSA). The comparative effectiveness of pharmacologic agents is …

An exploratory study on the association between serotonin and sleep breathing disorders

M Wieckiewicz, H Martynowicz, G Lavigne… - Scientific Reports, 2023 - nature.com
This exploratory observational study aimed to evaluate whether the blood levels of serotonin
and enzymes involved in serotonin synthesis are associated with sleep breathing …

Investigation and management of residual sleepiness in CPAP-treated patients with obstructive sleep apnoea: the European view

S Craig, JL Pépin, W Randerath… - European …, 2022 - Eur Respiratory Soc
Excessive daytime sleepiness (EDS) is a major symptom of obstructive sleep apnoea (OSA),
defined as the inability to stay awake during the day. Its clinical descriptors remain elusive …

Excessive daytime sleepiness: an emerging marker of cardiovascular risk

J Bock, N Covassin, V Somers - Heart, 2022 - heart.bmj.com
Excessive daytime sleepiness (EDS) is classically viewed as a consequence of insufficient
sleep or a symptom of sleep disorders. Epidemiological and clinical evidence have shown …

Residual excessive daytime sleepiness in patients treated for obstructive sleep apnea: guidance for assessment, diagnosis, and management

R Rosenberg, PK Schweitzer, J Steier… - Postgraduate …, 2021 - Taylor & Francis
Excessive daytime sleepiness (EDS) affects approximately half of patients with obstructive
sleep apnea (OSA) and can persist in some despite normalization of breathing, oxygenation …

Clinical and research solutions to manage obstructive sleep apnea: a review

F Xia, M Sawan - Sensors, 2021 - mdpi.com
Obstructive sleep apnea (OSA), a common sleep disorder disease, affects millions of
people. Without appropriate treatment, this disease can provoke several health-related risks …

Turning over a new leaf—pharmacologic therapy in obstructive sleep apnea

J Hedner, D Zou - Sleep Medicine Clinics, 2022 - sleep.theclinics.com
Obstructive sleep apnea (OSA) is a common condition that has turned out to provide a
challenge for physicians and the health-care systems. 1 This particular form of sleep …

Recommendations for clinical management of excessive daytime sleepiness in obstructive sleep apnoea–A Delphi consensus study

JS Steier, RK Bogan, IM Cano-Pumarega, JA Fleetham… - Sleep medicine, 2023 - Elsevier
Study objective Excessive daytime sleepiness is common with obstructive sleep apnoea and
can persist despite efforts to optimise primary airway therapy. The literature lacks …

Current management of residual excessive daytime sleepiness due to obstructive sleep apnea: insights for optimizing patient outcomes

R Mehra, R Heinzer, P Castillo - Neurology and Therapy, 2021 - Springer
Although excessive daytime sleepiness (EDS) attributable to obstructive sleep apnea (OSA)
can be resolved by consistent usage of and effective treatment (often with the use of …